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Role of protein kinase C in adriamycin-induced erythroid differentiation of K562 cells.
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Quercetin inhibits the growth of a multidrug-resistant estrogen-receptor-negative MCF-7 human breast-cancer cell line expressing type II estrogen-binding sites.槲皮素抑制表达II型雌激素结合位点的多药耐药雌激素受体阴性MCF-7人乳腺癌细胞系的生长。
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本文引用的文献

1
Phospholipid-sensitive Ca2+-dependent protein phosphorylation system in various types of leukemic cells from human patients and in human leukemic cell lines HL60 and K562, and its inhibition by alkyl-lysophospholipid.人类患者各类白血病细胞以及人白血病细胞系HL60和K562中的磷脂敏感型钙依赖性蛋白磷酸化系统,及其被烷基溶血磷脂抑制的情况。
Cancer Res. 1983 Jun;43(6):2955-61.
2
Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin.槲皮素对小鼠脑细胞溶胶中钙和磷脂依赖性蛋白激酶活性的抑制作用。
Biochem Biophys Res Commun. 1983 Dec 16;117(2):444-7. doi: 10.1016/0006-291x(83)91220-2.
3
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors.剂量-效应关系的定量分析:多种药物或酶抑制剂的联合效应
Adv Enzyme Regul. 1984;22:27-55. doi: 10.1016/0065-2571(84)90007-4.
4
The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitro and in vivo.槲皮素对劳氏肉瘤病毒转化基因产物在体外和体内磷酸化活性的影响。
Eur J Biochem. 1983 Oct 3;135(3):583-9. doi: 10.1111/j.1432-1033.1983.tb07692.x.
5
Perturbation of in vitro drug resistance in human lymphatic neoplasms by combinations of putative inhibitors of protein kinase C.蛋白激酶C假定抑制剂联合使用对人淋巴瘤体外耐药性的影响
Cancer Treat Rep. 1987 Dec;71(12):1239-43.
6
Comparative cytotoxicity of various drug combinations for human leukemic cells and normal hematopoietic precursors.多种药物组合对人白血病细胞和正常造血前体细胞的细胞毒性比较。
Cancer Res. 1987 Jan 1;47(1):119-22.
7
Triphenylethylenes: a new class of protein kinase C inhibitors.
J Natl Cancer Inst. 1986 Jun;76(6):1243-6.
8
Analysis of P210bcr-abl tyrosine protein kinase activity in various subtypes of Philadelphia chromosome-positive cells from chronic myelogenous leukemia patients.慢性粒细胞白血病患者费城染色体阳性细胞各亚型中P210bcr-abl酪氨酸蛋白激酶活性分析
Cancer Res. 1987 Mar 15;47(6):1731-9.
9
Preliminary observations on the therapy of the myeloid blast phase of chronic granulocytic leukemia with plicamycin and hydroxyurea.用普卡霉素和羟基脲治疗慢性粒细胞白血病髓系原始细胞期的初步观察
N Engl J Med. 1986 Dec 4;315(23):1433-8. doi: 10.1056/NEJM198612043152301.
10
Disposition of quercetin in man after single oral and intravenous doses.单次口服和静脉给药后槲皮素在人体内的处置情况。
Eur J Clin Pharmacol. 1975 Dec 19;9(2-3):229-34. doi: 10.1007/BF00614022.

Enhanced anti-proliferative action of busulphan by quercetin on the human leukaemia cell line K562.

作者信息

Hoffman R, Graham L, Newlands E S

机构信息

Cancer Research Campaign Laboratories, Department of Medical Oncology, Charing Cross Hospital, London, UK.

出版信息

Br J Cancer. 1989 Mar;59(3):347-8. doi: 10.1038/bjc.1989.68.

DOI:10.1038/bjc.1989.68
PMID:2930697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2247059/
Abstract
摘要