Romeo Umberto, Richetta Antonio, Rocchetti Federica, Macaluso Laura, Ciolfi Chiara, Gaimari Gianfranco, Caputo Martina, Tenore Gianluca, Brandi Marco, Palaia Gaspare, Polimeni Antonella
Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.
Department of Dermatology, Sapienza University of Rome, Rome, Italy.
Minerva Stomatol. 2018 Feb;67(1):12-19. doi: 10.23736/S0026-4970.17.04066-3.
The aim of this study was to investigate and compare the prevalence of oral mucosal lesions in a group of psoriatic patients and healthy subjects.
120 psoriatic patients were enrolled in this observational study. Clinical examination, panoramic X-ray, magnetic nuclear resonance of temporo-mandibular joint, parodontal evaluation, oropharyngeal buffer and incisional biopsies by scalpel, as applicable, were done in order to value the patients. The control group was formed by 201 non-psoriatic patients attending the hospital for dental conditions. Oral clinical evaluation of these patients was performed, to assess the presence of any oral manifestation that can be related to psoriasis: fissured tongue, geographic tongue, parodontitis, temporo-mandibular joint disorders and oral candidiasis. After the observational analysis, a statistical examination was conducted using the chi-square test (2-sided).
A percentage of 78.34% of patients belonging to the case group presented oral manifestations, while in the control group the 35.3% of the individuals presented any oral lesions. Especially geographic and fissured tongue showed a strong correlation with psoriasis.
Some oral mucosal lesions, such as geographic and fissured tongue, are strongly associated with psoriasis. Although these lesions are non-pathognomonic to psoriasis, their precise relationship needs to be clarified and further investigated.
本研究旨在调查并比较一组银屑病患者和健康受试者口腔黏膜病变的患病率。
120名银屑病患者纳入本观察性研究。根据情况,对患者进行临床检查、全景X线检查、颞下颌关节磁共振成像、牙周评估、口咽缓冲及手术刀切开活检,以评估患者情况。对照组由201名因牙齿问题到医院就诊的非银屑病患者组成。对这些患者进行口腔临床评估,以评估是否存在任何可能与银屑病相关的口腔表现:裂纹舌、地图舌、牙周炎、颞下颌关节紊乱和口腔念珠菌病。经过观察性分析后,使用卡方检验(双侧)进行统计学检验。
病例组中78.34%的患者有口腔表现,而对照组中35.3%的个体有任何口腔病变。特别是地图舌和裂纹舌与银屑病有很强的相关性。
一些口腔黏膜病变,如地图舌和裂纹舌,与银屑病密切相关。虽然这些病变并非银屑病所特有,但其确切关系有待阐明并进一步研究。