银屑病患者口腔病变的患病率。

Prevalence of oral lesions in patients with psoriasis.

作者信息

Hernández-Pérez Francisco, Jaimes-Aveldañez Alejandra, Urquizo-Ruvalcaba Ma de Lourdes, Díaz-Barcelot Moises, Irigoyen-Camacho Maria Esther, Vega-Memije Ma Elisa, Mosqueda-Taylor Adalberto

机构信息

Health Care Department, Universidad Autónoma Metropolitana, Xochimilco, México.

出版信息

Med Oral Patol Oral Cir Bucal. 2008 Nov 1;13(11):E703-8.

PMID:18978710

Abstract

AIM

To determine the prevalence of oral lesions (OL) in patients with psoriasis, and compare these findings with the ones found in patients without this condition.

MATERIALS AND METHODS

In the present observational and comparative study, we evaluated 207 patients, with and without psoriasis, attending the dermatological consulting service of a concentration hospital in Mexico City. The possible association between OL and psoriasis was analyzed through a logistic regression model; the Odds Ratio (OR) and its Confidence Interval (CI) was calculated to be 95%.

RESULTS

Two hundred and seven cases were examined (80 with psoriasis and 127 without psoriasis). Of these, 75 (36.2%) were men and 132 (63.7%) women. Oral lesions were found in 54 (67.5%) psoriatic patients and in 63 (49.6%) of the comparative group (p <0.012). Fissured tongue (FT) was present in 47.5 % of the patients with psoriasis and in 20.4 % of the group without psoriasis, (OR=3.46, 95% CI [1.14, 10.5], p=0.001). Geographic tongue (GT) was present in 12.5 % of the group with psoriasis and 4.7 % in the group without this disease (OR=3.54 95 % CI [1.97, 6.79], p=0.028). Likewise, six patients (7.5 %) with psoriasis and 3 (2.36 %) from the comparative group presented simultaneously GT and FT (p = 0.0776). The most frequent type of psoriasis was the vulgar psoriasis (90 %), in which a higher prevalence of FT (p <0.05) was present. There were no differences between both groups (p>0.05) regarding the use of tobacco. Alcohol consumption was greater (55.0%) among patients with psoriasis than among those without psoriasis (26.7%) (p<0.05), but when the association with GT and FT was analyzed, no significant differences were found among consumers and not consumers of tobacco and alcohol (p> 0.05).

CONCLUSIONS

The high prevalence of GT and FT in patients with psoriasis suggests that these lesions should be taken into account in new studies as possible predictors or markers of the severity of this dermatosis, in order to confirm the association of these entities.

摘要

目的

确定银屑病患者口腔病变（OL）的患病率，并将这些结果与无此疾病的患者的结果进行比较。

材料与方法

在本观察性和比较性研究中，我们评估了墨西哥城一家专科医院皮肤科咨询门诊的207例有或无银屑病的患者。通过逻辑回归模型分析OL与银屑病之间可能的关联；计算优势比（OR）及其95%置信区间（CI）。

结果

共检查了207例病例（80例银屑病患者和127例无银屑病患者）。其中，75例（36.2%）为男性，132例（63.7%）为女性。54例（67.5%）银屑病患者和63例（49.6%）对照组患者出现口腔病变（p<0.012）。47.5%的银屑病患者出现沟纹舌（FT），无银屑病组为20.4%（OR=3.46，95%CI[1.14,10.5]，p=0.001）。12.5%的银屑病组患者出现地图舌（GT），无此病组为4.7%（OR=3.54，9%CI[1.97,6.79]，p=0.028）。同样，6例（7.5%）银屑病患者和3例（2.36%）对照组患者同时出现GT和FT（p=0.0776）。最常见的银屑病类型是寻常型银屑病（90%），其中FT的患病率更高（p<0.05）。两组在吸烟方面无差异（p>0.05）。银屑病患者的饮酒率（55.0%）高于无银屑病患者（26.7%）（p<0.05），但在分析与GT和FT的关联时，吸烟和饮酒者与不吸烟者之间未发现显著差异（p>0.05）。