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胶原蛋白植入物和脐血单个核细胞可使脊髓损伤部位移除后后肢运动得以恢复。

Collagen Implant and Mononuclear Cells of Umbilical Blood Allow the Restore of Movements of Hind Limbs after Removing the Site of Spinal Cord.

作者信息

Ryabov S I, Zvyagintseva M A, Osidak E O, Smirnov V A

机构信息

National Medical Research Center for Cardiology of Ministry of Health of the Russian Federation, Moscow, Russia.

IMTEK Company, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2018 Jan;164(3):390-393. doi: 10.1007/s10517-018-3996-y. Epub 2018 Jan 8.

DOI:10.1007/s10517-018-3996-y
PMID:29308564
Abstract

Replacement of the removal site of the spinal cord on a collagen implant restores the motor function of the hind limbs in rats to the level of movements in the two joints for 8 weeks. After intravenous administration of mononuclear cells of human umbilical blood, recovery accelerated, significantly improved to the level of motion in the three joints, and there is a tendency to improve further recovery of movements.

摘要

在胶原蛋白植入物上替换脊髓切除部位可使大鼠后肢运动功能恢复至两个关节运动水平达8周。静脉注射人脐血单个核细胞后，恢复加速，显著改善至三个关节运动水平，且有进一步改善运动恢复的趋势。

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