School of Social Work, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA; New York State Psychiatric Institute, New York, NY, USA.
Drug Alcohol Depend. 2023 Jul 1;248:109940. doi: 10.1016/j.drugalcdep.2023.109940. Epub 2023 May 22.
Cannabis use and cannabis use disorder (CUD) are associated with mental health disorders, however the extent of this matter among pregnant and recently postpartum (e.g., new moms) women in the US is unknown. Associations between cannabis use, DSM-5 CUD and DSM-5 mental health disorders (mood, anxiety, personality and post-traumatic stress disorders) were examined among a nationally representative sample of pregnant and postpartum women.
The 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III was used to examine associations between past-year cannabis use, CUD and mental health disorders. Weighted logistic regression models were used to estimate unadjusted and adjusted odds ratios (aORs). The sample (N=1316) included 414 pregnant and 902 postpartum women (pregnant in the past year), aged 18-44 years old.
The prevalence of past-year cannabis use and CUD was 9.8% and 3.2%, respectively. The odds of cannabis use (aORs range 2.10-3.87, p-values<0.01) and CUD (aORs range 2.55-10.44, p-values< 0.01) were higher among women with versus without any past-year mood, anxiety or posttraumatic stress disorders or any lifetime personality disorder. aORs for the association of cannabis use with specific mood, anxiety or personality disorders ranged from 1.95 to 6.00 (p-values<0.05). aORs for the association of CUD with specific mood, anxiety or personality disorders ranged from 2.36 to 11.60 (p-values<0.05).
From pregnancy up to one year postpartum is a critical period where women may be particularly vulnerable to mental health disorders, cannabis use and CUD. Treatment and prevention are essential.
大麻使用和大麻使用障碍（CUD）与心理健康障碍有关，然而，在美国怀孕和产后（例如，新妈妈）女性中，这种情况的程度尚不清楚。在一个具有全国代表性的孕妇和产后妇女样本中，研究了大麻使用、DSM-5 CUD 和 DSM-5 心理健康障碍（情绪、焦虑、人格和创伤后应激障碍）之间的关联。
使用 2012-2013 年全国酒精相关情况和条件 III 流行病学调查来研究过去一年大麻使用、CUD 和心理健康障碍之间的关联。使用加权逻辑回归模型来估计未调整和调整后的优势比（aOR）。该样本（N=1316）包括 414 名孕妇和 902 名产后妇女（过去一年怀孕），年龄在 18-44 岁之间。
过去一年大麻使用和 CUD 的患病率分别为 9.8%和 3.2%。与没有任何过去一年的情绪、焦虑或创伤后应激障碍或任何终身人格障碍的女性相比，大麻使用（aOR 范围为 2.10-3.87，p 值<0.01）和 CUD（aOR 范围为 2.55-10.44，p 值<0.01）的可能性更高。大麻使用与特定情绪、焦虑或人格障碍的关联的 aOR 范围为 1.95 至 6.00（p 值<0.05）。CUD 与特定情绪、焦虑或人格障碍的关联的 aOR 范围为 2.36 至 11.60（p 值<0.05）。
从怀孕到产后一年是一个关键时期，女性在此期间可能特别容易受到心理健康障碍、大麻使用和 CUD 的影响。治疗和预防至关重要。
