Tynan M
Department of Paediatric Cardiology, United Medical School, Guy's Hospital, London.
Herz. 1988 Apr;13(2):59-70.
Balloon angioplasty and valvuloplasty offer an alternative to surgery in many congenital cardiac conditions and are a useful adjunct in others. To yield optimal results, the most desirable improvement in hemodynamics with the least amount of damage to normal tissue, choice of the catheter should take into consideration the size of the balloon, type of shaft and shape of the balloon. Experience has shown that dilatation is best achieved when the size of the balloon is such that there is a combination of circumferential force, the stress exerted when the balloon is near its maximal diameter, and longitudinal force, the extent of which is directly proportional to the deformity of the balloon. If the balloon is too small, little benefit may be accrued from the procedure; if it is too large, there is a risk of danger to adjacent normal structures. A stiff shaft helps to maintain a stable position during inflation and the size of the shaft determines the caliber of the guidewire lumen and the inflation/deflation lumen. A single, circular balloon has the advantage of distributing the dilating forces uniformly during inflation; more recently introduced alternative designs with two or three balloons mounted around the shaft have the advantage of allowing some blood flow to occur even at full inflation but they also have the theoretical disadvantage of not ensuring an even distribution of circumferential force. Dilatation of pulmonary valve stenosis may be considered indicated in the presence of a pressure gradient of 40 mm Hg with a right ventricular pressure of 60 mm Hg as the lower limit. In the newborn, this may be qualified by setting the lower limit of right ventricular pressure as 10 mm Hg below systemic arterial pressure if that is 60 mm Hg or less. On choice of the proper balloon size, approximately 20 to 30 percent greater than the pulmonary root, success may be expected in 90% of the cases and, in general, the initial result appears to be that which persists. Although Doppler echocardiography frequently shows pulmonary regurgitation, this is rarely clinically evident. The procedure is safe and only few complications have been reported. Establishing the indication for aortic valvuloplasty usually requires the presence of a systolic gradient of 60 mm Hg without severe regurgitation; mild aortic regurgitation is not a contraindication to the procedure. Reports have indicated good results in both infants and children. This procedure is not without risk and deaths have been reported.(ABSTRACT TRUNCATED AT 400 WORDS)
在许多先天性心脏病中,球囊血管成形术和瓣膜成形术为手术提供了一种替代方案,在其他一些疾病中也是一种有用的辅助手段。为了获得最佳效果,即实现最理想的血流动力学改善,同时对正常组织造成的损伤最小,导管的选择应考虑球囊大小、导管杆类型和球囊形状。经验表明,当球囊大小能使圆周力(球囊接近最大直径时施加的应力)和纵向力(其程度与球囊变形直接成正比)相结合时,扩张效果最佳。如果球囊太小,该操作可能获益甚微;如果太大,则有危及相邻正常结构的风险。硬导管杆有助于在充盈过程中保持稳定位置,导管杆的大小决定了导丝腔和充放气腔的内径。单个圆形球囊的优点是在充盈时能均匀分布扩张力;最近推出的在导管杆周围安装两个或三个球囊的替代设计,其优点是即使在完全充盈时也能允许一些血流通过,但理论上也有不能确保圆周力均匀分布的缺点。当肺动脉瓣狭窄存在40毫米汞柱的压力阶差,且右心室压力下限为60毫米汞柱时,可考虑进行肺动脉瓣扩张术。在新生儿中,如果体动脉压为60毫米汞柱或更低,则将右心室压力下限设定为比体动脉压低10毫米汞柱。选择合适的球囊大小,即比肺动脉根部大约大20%至30%,90%的病例可能会成功,一般来说,初始结果似乎会持续存在。虽然多普勒超声心动图经常显示肺动脉反流,但临床上很少明显。该操作是安全的,报告的并发症很少。确定主动脉瓣成形术的指征通常需要存在60毫米汞柱的收缩期压力阶差且无严重反流;轻度主动脉反流不是该操作的禁忌证。报告表明,该操作在婴儿和儿童中均有良好效果。此操作并非没有风险,也有死亡报告。(摘要截选至400字)