Mitchell Ian, Defoy Isabelle, Grubb ElizaBeth
Alberta Children's Hospital, 2888 Shaganappi Trail NW, Calgary, AB, Canada T6B 6A8.
AbbVie Corporation, 8401 Trans-Canada Highway, Saint-Laurent, QC, Canada H4S 1Z1.
Can Respir J. 2017;2017:4521302. doi: 10.1155/2017/4521302. Epub 2017 Nov 7.
To examine the socioeconomic burden of respiratory syncytial virus (RSV) disease for Canadian infants hospitalized for the condition.
The descriptive study used data collected in Alberta, Canada, during 2 consecutive RSV seasons. Infants (<1 year of age) were included if they had not received palivizumab and were hospitalized with a confirmed diagnosis of RSV. Hospitalization resource use and parental time burden, out-of-pocket costs, lost work productivity, and stress and anxiety were assessed.
13.4% of all infants ( = 67) had intensive care unit (ICU) admission, and average ICU stay for these infants was 6.5 days. Families had average out-of-pocket expenses of 736.69 Canadian dollars (CAD $), and the average time both parents spent in hospital was nearly 7 days (164.0 hours). For working parents ( = 43), average absenteeism was 49% and overall work impairment was 77.8%. Parents also exhibited significant parental stress (3.6 on the Parental Stressor Scale: 43.9 state anxiety and 36.9 trait anxiety scores).
Results indicate a high burden associated with the hospitalization of an infant due to RSV disease in terms of resource use, time, productivity, costs, and stress, even among a population of infants not considered to be at risk for the condition.
研究呼吸道合胞病毒（RSV）疾病给因该疾病住院的加拿大婴儿带来的社会经济负担。
这项描述性研究使用了加拿大艾伯塔省在连续两个RSV流行季节收集的数据。纳入未接受帕利珠单抗治疗且确诊为RSV感染而住院的1岁以下婴儿。评估了住院资源使用情况、父母的时间负担、自付费用、工作生产力损失以及压力和焦虑情况。
所有婴儿中13.4%（n = 67）入住了重症监护病房（ICU），这些婴儿在ICU的平均住院时间为6.5天。家庭平均自付费用为736.69加元（CAD $），父母双方在医院花费的平均时间接近7天（164.0小时）。对于有工作的父母（n = 43），平均缺勤率为49%，总体工作受损率为77.8%。父母还表现出显著的父母压力（父母压力量表评分为3.6：状态焦虑得分43.9，特质焦虑得分36.9）。
结果表明，即使在被认为没有该疾病风险的婴儿群体中，因RSV疾病导致婴儿住院在资源使用、时间、生产力、成本和压力方面也会带来很高的负担。
