Rao D C, Keats B J, Lalouel J M, Morton N E, Yee S
Am J Hum Genet. 1979 Nov;31(6):680-96.
Thirteen loci are mapped on chromosome 1 from genetic evidence. The maximum likelihood map presented permits confirmation that Scianna (SC) and a fourteenth locus, phenylketonuria (PKU), are on chromosome 1, although the location of the latter on the PGM1-AMY segment is uncertain. Eight other controversial genetic assignments are rejected, providing a practical demonstration of the resolution which maximum likelihood theory brings to mapping.
根据遗传证据,13个基因座被定位在1号染色体上。所呈现的最大似然图谱证实了斯恰纳血型(SC)和第14个基因座苯丙酮尿症(PKU)位于1号染色体上,尽管后者在磷酸葡萄糖变位酶1-淀粉酶(PGM1-AMY)片段上的位置尚不确定。另外8个有争议的基因定位被否定,这实际证明了最大似然理论在基因定位方面所带来的分辨率。