Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
University of Michigan C.S. Mott Children's Hospital Congenital Heart Center, Ann Arbor, MI, USA.
J Cardiovasc Transl Res. 2018 Apr;11(2):145-155. doi: 10.1007/s12265-017-9781-x. Epub 2018 Jan 8.
Computational fluid dynamics (CFD) is a modeling technique that enables calculation of the behavior of fluid flows in complex geometries. In cardiovascular medicine, CFD methods are being used to calculate patient-specific hemodynamics for a variety of applications, such as disease research, noninvasive diagnostics, medical device evaluation, and surgical planning. This paper provides a concise overview of the methods to perform patient-specific computational analyses using clinical data, followed by a case study where CFD-supported surgical planning is presented in a patient with Fontan circulation complicated by unilateral pulmonary arteriovenous malformations. In closing, the challenges for implementation and adoption of CFD modeling in clinical practice are discussed.
计算流体动力学（CFD）是一种建模技术，可用于计算复杂几何形状中的流体流动行为。在心血管医学中，CFD 方法正被用于计算各种应用的患者特异性血液动力学，例如疾病研究、非侵入性诊断、医疗器械评估和手术规划。本文提供了使用临床数据进行患者特异性计算分析的方法概述，然后通过一个病例研究，介绍了在 Fontan 循环合并单侧肺动静脉畸形的患者中，CFD 支持的手术规划。最后，讨论了 CFD 建模在临床实践中的实施和采用所面临的挑战。
