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患者特定的血液动力学建模:在 Fontan 循环矫正中支持手术规划。

Patient-Specific Modeling of Hemodynamics: Supporting Surgical Planning in a Fontan Circulation Correction.

机构信息

Department of Surgery, University of Michigan, Ann Arbor, MI, USA.

University of Michigan C.S. Mott Children's Hospital Congenital Heart Center, Ann Arbor, MI, USA.

出版信息

J Cardiovasc Transl Res. 2018 Apr;11(2):145-155. doi: 10.1007/s12265-017-9781-x. Epub 2018 Jan 8.

Abstract

Computational fluid dynamics (CFD) is a modeling technique that enables calculation of the behavior of fluid flows in complex geometries. In cardiovascular medicine, CFD methods are being used to calculate patient-specific hemodynamics for a variety of applications, such as disease research, noninvasive diagnostics, medical device evaluation, and surgical planning. This paper provides a concise overview of the methods to perform patient-specific computational analyses using clinical data, followed by a case study where CFD-supported surgical planning is presented in a patient with Fontan circulation complicated by unilateral pulmonary arteriovenous malformations. In closing, the challenges for implementation and adoption of CFD modeling in clinical practice are discussed.

摘要

计算流体动力学(CFD)是一种建模技术,可用于计算复杂几何形状中的流体流动行为。在心血管医学中,CFD 方法正被用于计算各种应用的患者特异性血液动力学,例如疾病研究、非侵入性诊断、医疗器械评估和手术规划。本文提供了使用临床数据进行患者特异性计算分析的方法概述,然后通过一个病例研究,介绍了在 Fontan 循环合并单侧肺动静脉畸形的患者中,CFD 支持的手术规划。最后,讨论了 CFD 建模在临床实践中的实施和采用所面临的挑战。

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