Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, NC.
Department of Population Health Sciences, School of Medicine, Duke University Medical Center, Durham, NC.
Health Serv Res. 2018 Aug;53 Suppl 1(Suppl Suppl 1):3125-3147. doi: 10.1111/1475-6773.12815. Epub 2018 Jan 8.
To compare different strategies for analyzing longitudinal expenditure data that have a point mass at $0. We provide guidance on parameter interpretation, research questions, and model selection.
DATA SOURCES, STUDY DESIGN, AND DATA COLLECTION: One-part models, uncorrelated two-part models, correlated conditional two-part (CTP) models, and correlated marginalized two-part (MTP) models have been proposed for longitudinal expenditures that often exhibit a large proportion of zeros and a distribution of continuous, highly right-skewed positive values. Guidance on implementing and interpreting each of these model is illustrated with an example of longitudinal (2000-2003) specialty care expenditures of veterans with hypertension, drawn from Veterans Administration data.
The four strategies answer different research questions, are appropriate for different structures of data, and provide different results. If there is a point mass at $0, then the MTP model may be most useful if the primary interest is in mean expenditures of the entire population. A CTP model may be most useful if the primary interest is in the level of expenditures conditional on them being incurred.
Researchers should consider which modeling strategy for longitudinal expenditure outcomes is both consistent with research aims and appropriate for the data at hand.
比较具有 0 点质量的纵向支出数据的不同分析策略。我们提供参数解释、研究问题和模型选择方面的指导。
数据来源、研究设计和数据收集:对于经常表现出大量零值和连续、高度右偏正分布值的纵向支出,已经提出了单部分模型、不相关两部分模型、相关条件两部分 (CTP) 模型和相关边际两部分 (MTP) 模型。我们通过来自退伍军人事务部数据的高血压退伍军人的纵向(2000-2003 年)专科护理支出的示例来说明实施和解释每种模型的指南。
这四种策略回答了不同的研究问题,适用于不同结构的数据,并提供了不同的结果。如果存在 0 点质量,那么如果主要关注整个人群的平均支出,那么 MTP 模型可能最有用。如果主要关注支出水平,则 CTP 模型可能最有用。
研究人员应考虑用于纵向支出结果的建模策略,该策略既要与研究目标一致,又要适应当前的数据。