伴有肉瘤过度生长的子宫腺肉瘤：一名16岁女孩侵袭性疾病的病例报告及文献综述
Uterine Adenosarcoma with Sarcomatous Overgrowth: A Case Report of Aggressive Disease in a 16-Year-Old Girl and a Literature Review.
作者信息
Liu Hanyuan, Shen Zhen, Wu Dabao, Zhou Ying
机构信息
Department of Obstetrics and Gynecology, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, PR China.
Department of Obstetrics and Gynecology, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, PR China.
出版信息
J Pediatr Adolesc Gynecol. 2018 Aug;31(4):426-431. doi: 10.1016/j.jpag.2017.12.012. Epub 2018 Jan 6.
BACKGROUND
Uterine adenosarcoma with sarcomatous overgrowth (ASSO) is a rare and aggressive disease. A case of a 16-year-old girl with uterine ASSO is reported herein. The patient received surgical resection and chemotherapy and remained alive without disease 11 months after the surgery.
CASE
A 16-year-old girl was diagnosed with uterine ASSO, International Federation of Gynecology and Obstetrics (2009) stage I c. She underwent total abdominal hysterectomy, bilateral salpingectomy, and chemotherapy. She remains alive and there was no evidence of tumor recurrence on follow-up physical, laboratory, and ultrasound scan examinations.
SUMMARY AND CONCLUSION
Surgery is the primary treatment for uterine ASSO, total abdominal or laparoscopic-assisted vaginal hysterectomy with or without bilateral salpingo-oophorectomy are recommended. Early surgical resection might increase survival of uterine adenosarcoma. Long-term follow-up of the patients is recommended because of the high chance of recurrence.
背景
伴有肉瘤过度生长的子宫腺肉瘤（ASSO）是一种罕见且侵袭性强的疾病。本文报道了一例16岁患有子宫ASSO的女孩。该患者接受了手术切除和化疗，术后11个月仍无疾病存活。
病例
一名16岁女孩被诊断为子宫ASSO，国际妇产科联盟（2009年）I c期。她接受了全腹子宫切除术、双侧输卵管切除术和化疗。她仍然存活，随访的体格检查、实验室检查和超声扫描均未发现肿瘤复发迹象。
总结与结论
手术是子宫ASSO的主要治疗方法，推荐行全腹或腹腔镜辅助阴道子宫切除术，可同时或不同时行双侧输卵管卵巢切除术。早期手术切除可能提高子宫腺肉瘤患者的生存率。鉴于复发几率高，建议对患者进行长期随访。
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