新生儿中、重度缺氧缺血性脑病的亚低温治疗
Mild Hypothermia Therapy for Moderate or Severe Hypoxicischemic Encephalopathy in Neonates.
作者信息
Liao Weihua, Xu Huiying, Ding Jing, Huang Hong
机构信息
Dept. of Neonatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
出版信息
Iran J Public Health. 2018 Jan;47(1):64-69.
BACKGROUND
To study the nursing method of mild hypothermia therapy for moderate or severe hypoxic-ischemic encephalopathy (HIE) in neonates.
METHODS
According to the inclusion and exclusion criteria, 48 patients were selected from Nanfang Hospital from December 2015 to October 2016 and randomly divided into the control group (n=24) and observation group (n=24). The control group received routine treatment and nursing, while the observation group received the same treatment as the control group combined with mild hypothermia treatment and nursing. The clinical effects were compared.
RESULTS
The total effective rate in the observation group was increased and mortality was decreased, and the differences were statistically significant (=0.029 and 0.033, respectively). The 28 d neonatal behavioral neurological assessment and nursing satisfaction scores in the observation group were higher than those in the control group, and the differences were statistically significant (=0.017 and 0.008, respectively).
CONCLUSION
Mild hypothermia therapy for moderate or severe HIE in neonates is safe and effective, and the correct nursing method is important for guaranteeing proper clinical treatment.
背景
探讨新生儿中重度缺氧缺血性脑病（HIE）亚低温治疗的护理方法。
方法
根据纳入和排除标准，选取2015年12月至2016年10月南方医院收治的48例患者，随机分为对照组（n = 24）和观察组（n = 24）。对照组给予常规治疗和护理，观察组在对照组治疗基础上联合亚低温治疗及护理。比较两组临床疗效。
结果
观察组总有效率提高，死亡率降低，差异有统计学意义（分别为=0.029和0.033）。观察组28 d新生儿行为神经评分及护理满意度评分均高于对照组，差异有统计学意义（分别为=0.017和0.008）。
结论
新生儿中重度HIE亚低温治疗安全有效，正确的护理方法对保证临床治疗效果至关重要。
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