Silva Maria Michelle Pereira, Aguiar Maria Isis Freire de, Rodrigues Andrea Bezerra, Miranda Maira Di Ciero, Araújo Michell Ângelo Marques, Rolim Isaura Letícia Tavares Palmeira, Souza Angela Maria Alves E
Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil.
Universidade Federal do Maranhão, Departamento de Enfermagem, São Luís, MA, Brasil.
Rev Esc Enferm USP. 2018 Jan 8;51:e03272. doi: 10.1590/S1980-220X2016043503272.
To analyze the effects of nanoparticle-based dressings on the wound healing process in in vitro animals and human cells based on scientific evidence.
A systematic review of the literature in LILACS, PubMed and Science Direct databases. The articles were selected and evaluated for the level of evidence by the application of STROBE.
The sample consisted of 12 articles. The application of the products occurred in surgical wounds, burns, infected wounds and gingival ulcers in laboratory animals, as well as in vitro tests, demonstrating that among other advantages, the nanoparticle-based dressings increased the healing speed, had good antibacterial capacity and were non cytotoxic agents.
Based on the analyzed articles, it can be affirmed that dressings containing nanocomposites are quite promising and are shown as a great therapeutic option in wound healing.
基于科学证据分析纳米颗粒敷料对体外动物和人类细胞伤口愈合过程的影响。
对LILACS、PubMed和Science Direct数据库中的文献进行系统综述。通过应用STROBE对文章进行筛选和证据水平评估。
样本包括12篇文章。这些产品应用于实验动物的手术伤口、烧伤、感染伤口和牙龈溃疡以及体外试验，表明基于纳米颗粒的敷料除其他优点外，还能提高愈合速度，具有良好的抗菌能力且无细胞毒性。
基于所分析的文章，可以肯定含有纳米复合材料的敷料很有前景，是伤口愈合中一种很好的治疗选择。
