Spencer James M, Accioly Julianna, Kitchen Neal
J Drugs Dermatol. 2018 Jan 1;17(1):113-115.
Melasma remains a troubling problem for physicans and patients alike. It is a chronic irregular, symmetric hyperpigmentation seen most often in women. In this study, a unique combination of ingredients with non-irritating properties was tested for treatment of melasma. In a double blind, placebo controlled, split face trial, 17 patients with melasma were treated on one half of the face, left or right, while the other received placebo control. All patients used sunscreen on both sides. Measurement with a colorimeter (Mexameter) was taken at baseline and after 8 weeks of daily use. The active side showed an objective decrease in hyperpigmentation of 14.60% while the control side showed a decrease of 9.82%. We conclude the product provides a non-irritating effective therapy for melasma.
J Drugs Dermatol. 2018;17(1):113-115.
.黄褐斑对医生和患者来说都是一个棘手的问题。它是一种慢性、不规则、对称的色素沉着过度，多见于女性。在本研究中，测试了一种具有无刺激性特性的独特成分组合用于治疗黄褐斑。在一项双盲、安慰剂对照、半脸试验中，17名黄褐斑患者的一侧面部（左侧或右侧）接受治疗，而另一侧接受安慰剂对照。所有患者两侧面部均使用防晒霜。在基线时以及每日使用8周后，使用色度仪（Mexameter）进行测量。治疗组面部色素沉着过度客观上减少了14.60%，而对照组减少了9.82%。我们得出结论，该产品为黄褐斑提供了一种无刺激性的有效治疗方法。
《皮肤药物学杂志》。2018年；17(1):113 - 115。
