Coronel Institute of Occupational Health, Amsterdam Public Health research institute, Academic Medical Center, P.O. box 22660, 1100, DD, Amsterdam, the Netherlands.
Department of Head and Neck Surgical Oncology, UMC Utrecht Cancer Center, University Medical Center Utrecht, P.O. box 85500, 3508, GA, Utrecht, the Netherlands.
BMC Cancer. 2018 Jan 10;18(1):66. doi: 10.1186/s12885-017-3966-1.
To assess the factorial structure, internal consistency, construct validity and reproducibility of the Quality of Working Life Questionnaire for Cancer Survivors (QWLQ-CS).
An Exploratory Factor Analysis (EFA) was performed on QWLQ-CS data from a sample of employed cancer survivors to establish the final number of items and factorial structure of the QWLQ-CS. Internal consistency was assessed using Cronbach's alpha. In a second sample of (self-)employed cancer survivors, construct validity was tested by convergent validity (correlations of QWLQ-CS with construct-related questionnaires), and discriminative validity (difference in QWLQ-CS scores between cancer survivors and employed people without cancer). In a subgroup of stable cancer survivors subtracted from the second sample, reproducibility was evaluated by Intraclass Correlation Coefficient (ICC) and Standard Error of Measurement (SEM).
EFA on QWLQ-CS data of 302 cancer survivors resulted in 23 items and five factors. The internal consistency of the QWLQ-CS was Cronbach's α = 0.91. Convergent validity on data of 130 cancer survivors resulted in r = 0.61-0.70. QWLQ-CS scores of these cancer survivors statistically differed (p = 0.04) from employed people without cancer (N = 45). Reproducibility of QWLQ-CS data from 87 cancer survivors demonstrated an ICC of 0.84 and a SEM of 9.59.
The five-factor QWLQ-CS with 23 items and adequate internal consistency, construct validity, and reproducibility at group level can be used in clinical and occupational healthcare, and research settings.
评估癌症幸存者工作生活质量问卷（QWLQ-CS）的因子结构、内部一致性、构念效度和可重复性。
对一组在职癌症幸存者的 QWLQ-CS 数据进行探索性因素分析（EFA），以确定 QWLQ-CS 的最终项目数和因子结构。采用 Cronbach's alpha 评估内部一致性。在第二组（自我）在职癌症幸存者样本中，通过收敛效度（QWLQ-CS 与结构相关问卷的相关性）和判别效度（癌症幸存者与无癌症在职人员的 QWLQ-CS 评分差异）来检验构念效度。在从第二组样本中减去稳定癌症幸存者的亚组中，通过组内相关系数（ICC）和测量标准误差（SEM）评估可重复性。
对 302 例癌症幸存者的 QWLQ-CS 数据进行 EFA，得出 23 个项目和 5 个因子。QWLQ-CS 的内部一致性为 Cronbach's α=0.91。对 130 例癌症幸存者的数据进行收敛效度分析，得出 r=0.61-0.70。这些癌症幸存者的 QWLQ-CS 评分与无癌症的在职人员（N=45）存在统计学差异（p=0.04）。来自 87 例癌症幸存者的 QWLQ-CS 数据的可重复性显示 ICC 为 0.84，SEM 为 9.59。
具有 23 个项目和足够内部一致性、构念效度和组水平可重复性的五因素 QWLQ-CS 可用于临床和职业保健以及研究环境。
