Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Capital Medical University, Beijing, China.
Allergy. 2018 Jun;73(6):1232-1243. doi: 10.1111/all.13388. Epub 2018 Mar 23.
The aim of this study was to investigate the prevalence of epidemiologic and physician-diagnosed pollen-induced AR (PiAR) in the grasslands of northern China and to study the impact of the intensity and time of pollen exposure on PiAR prevalence.
A multistage, clustered and proportionately stratified random sampling with a field interviewer-administered survey study was performed together with skin prick tests (SPT) and measurements of the daily pollen count.
A total of 6043 subjects completed the study, with a proportion of 32.4% epidemiologic AR and 18.5% PiAR. The prevalence was higher in males than females (19.6% vs 17.4%, P = .024), but no difference between the two major residential and ethnic groups (Han and Mongolian) was observed. Subjects from urban areas showed higher prevalence of PiAR than rural areas (23.1% vs 14.0%, P < .001). Most PiAR patients were sensitized to two or more pollens (79.4%) with artemisia, chenopodium, and humulus scandens being the most common pollen types, which were similarly found as the top three sensitizing pollen allergens by SPT. There were significant regional differences in the prevalence of epidemiologic AR (from 18.6% to 52.9%) and PiAR (from 10.5% to 31.4%) among the six areas investigated. PiAR symptoms were positively associated with pollen counts, temperature, and precipitation (P < .05), but negatively with wind speed and pressure P < .05).
Pollen-induced AR (PiAR) prevalence in the investigated region is extremely high due to high seasonal pollen exposure, which was influenced by local environmental and climate conditions.
本研究旨在调查中国北方草原地区流行病学和医生诊断的花粉致敏性变应性鼻炎（PiAR）的流行情况，并研究花粉暴露强度和时间对 PiAR 流行率的影响。
采用多阶段、聚类和比例分层随机抽样方法，结合现场访谈员管理的调查研究、皮肤点刺试验（SPT）和每日花粉计数测量进行。
共有 6043 名受试者完成了研究，其中流行病学变应性鼻炎的比例为 32.4%，花粉致敏性变应性鼻炎的比例为 18.5%。男性的患病率高于女性（19.6%比 17.4%，P=0.024），但两个主要居住和民族群体（汉族和蒙古族）之间没有差异。城市地区的受试者比农村地区的受试者更易患 PiAR（23.1%比 14.0%，P<0.001）。大多数 PiAR 患者对两种或更多种花粉过敏（79.4%），蒿属、藜科和葎草是最常见的花粉类型，与 SPT 发现的三种最常见致敏花粉过敏原相似。在所调查的六个地区，流行病学变应性鼻炎（从 18.6%到 52.9%）和花粉致敏性变应性鼻炎（从 10.5%到 31.4%）的流行率存在显著的地区差异。PiAR 症状与花粉计数、温度和降水呈正相关（P<0.05），与风速和气压呈负相关（P<0.05）。
由于季节性花粉暴露高，该地区花粉致敏性变应性鼻炎（PiAR）的患病率极高，这受到当地环境和气候条件的影响。
Zotero 插件
