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免疫功能正常患者的侵袭性曲霉性假膜性和阻塞性气管支气管炎

Invasive Aspergillus Pseudomembranous and Obstructive Tracheo-bronchitis in an Immuno-competent Patient.

作者信息

Pal Ramesh S, Spalgais Sonam, Murar Amit Kumar, Ojha Umesh Chandra

机构信息

Consultant.

Senior Resident, ESI-PGIMSR New Delhi.

出版信息

J Assoc Physicians India. 2017 Nov;65(11):92-93.

Abstract

A 19 year female, presented with life threatening haemoptysis and cough with minimum expectoration for 3 months. Bronchoscopy showed multiple nodules in airway. The direct microscopy and culture of sputum revealed fungal elements and Aspergillus flavus respectively. Serum Galactomannan was positive. Thus diagnosis of invasive aspergillus tracheo-bronchitis made. She responded to voriconazole. Aspergillus tracheo-bronchitis is a rare form of invasive pulmonary aspergillosis in immuno-competent host. Aspergillus spp in respiratory samples should not be routinely discarded as colonization.

摘要

一名19岁女性,出现危及生命的咯血和咳嗽,咳痰极少,持续3个月。支气管镜检查显示气道内有多个结节。痰直接镜检和培养分别发现真菌成分和黄曲霉。血清半乳甘露聚糖呈阳性。由此诊断为侵袭性曲霉气管支气管炎。她对伏立康唑有反应。曲霉气管支气管炎是免疫功能正常宿主中侵袭性肺曲霉病的一种罕见形式。呼吸道样本中的曲霉属不应作为定植菌而常规丢弃。

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