Pradhan Dinesh, Quiroga-Garza Gabriela, Hrebinko Ronald, Dhir Rajiv, Parwani Anil V
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Indian J Pathol Microbiol. 2017 Oct-Dec;60(4):571-573. doi: 10.4103/IJPM.IJPM_618_16.
Epidermoid cyst of the renal pelvis is exceptionally rare. The histogenetic mechanism has not been well characterized. Herein, we report a case of intrarenal epidermoid cyst in a 62-year-old woman who had undergone left nephrolithotomy for a staghorn calculus. She was being followed up for bilateral renal cysts when a complex mass was noted arising from the lower pole of the left kidney. Renal ultrasound showed a small left kidney with a solid vascular echogenic mass. A laparoscopic radical nephrectomy was performed. Gross examination revealed a well-circumscribed cystic mass with friable tan-yellow contents. Microscopically, a cystic structure lined by mature epidermis without atypia indicating epidermoid cyst was noted. The lesion appeared to be in continuity with the pelvicalyceal urothelium which displayed extensive squamous metaplasia. The patient is disease free and is doing well. Better clinical awareness of this benign entity and a preoperative biopsy may help preserve a kidney.
肾盂表皮样囊肿极为罕见。其组织发生机制尚未完全明确。在此，我们报告一例62岁女性的肾内表皮样囊肿病例，该患者因鹿角形结石接受了左肾切开取石术。在对其双侧肾囊肿进行随访时，发现左肾下极出现一个复杂肿块。肾脏超声显示左肾较小，有一个实性血管性回声肿块。遂行腹腔镜根治性肾切除术。大体检查发现一个边界清晰的囊性肿块，内容物为易碎的棕黄色。显微镜下可见一个由成熟表皮内衬的囊性结构，无异型性，提示为表皮样囊肿。病变似乎与肾盂输尿管上皮连续，后者显示广泛的鳞状化生。患者无疾病复发，情况良好。提高对这种良性病变的临床认识以及术前活检可能有助于保留肾脏。
