用一种实验性的晶须增强非创伤性修复治疗复合材料对天然人牙本质龋损进行再矿化。

Remineralization of Natural Human Carious Dentin Lesions with an Experimental Whisker-Reinforced Atraumatic Restorative Treatment Composite.

机构信息

The State Key Laboratory Breeding Base of Basic Science of Stomatology, Hubei Province and Key Laboratory of Oral Biomedicine, Ministry of Education (Hubei-MOST KLOS & KLOBME), School and Hospital of Stomatology, Wuhan University, Wuhan, China.

Restorative Department, College of Dentistry, University of Illinois at Chicago, Chicago, IL.

出版信息

J Prosthodont. 2019 Oct;28(8):920-926. doi: 10.1111/jopr.12754. Epub 2018 Jan 11.

DOI:10.1111/jopr.12754

PMID:29323776

Abstract

PURPOSE

To evaluate the remineralization of natural human dentin caries with an experimental whisker-reinforced Atraumatic Restorative Treatment (ART) composite.

MATERIALS AND METHODS

Teeth with moderate active dentin caries were prepared with caries-disclosing dye and hand instruments, restored with ART or resin-modified glass ionomer cement (RM-GIC), and then wet sliced into 120-µm sections with 15 sections in each group. After taking transverse microradiographs and implementing digital image analysis to determine the "mineral-loss-before," each section was incubated in artificial saliva solution (pH = 7.0) for 4 weeks and 8 weeks with 1 hour each workday in demineralization solution (pH = 4.3). Transverse microradiographs of each section were retaken, and the "mineral-loss-after" was determined. The remineralization was calculated from [1-("mineral-loss-after"/"mineral-loss-before")] × 100%. Results were statistically analyzed with a repeated-measures ANOVA with one within-subject factor (time: 4 and 8 weeks) and one between-subject factor (material: ART and RM-GIC) (α = 0.05).

RESULTS

The statistical analysis indicated that ART composite resulted in significantly higher remineralization than the RM-GIC (p ≤ 0.05). For the remineralization of each material, there was a statistical difference between 4 weeks and 8 weeks (p ≤ 0.05).

CONCLUSIONS

This experimental ART composite remineralized natural human dentin caries better than the RM-GIC.

摘要

目的

评估一种实验性的纤维增强微创修复材料（ART）复合树脂对天然人牙本质龋再矿化的效果。

材料和方法

使用龋显色剂和手动器械对具有中度活跃性牙本质龋的牙齿进行制备，用 ART 或树脂改良型玻璃离子水门汀（RM-GIC）进行修复，然后用湿切片机将每组 120μm 厚的 15 个切片。在进行横向显微射线照相术并进行数字图像分析以确定“矿化损失前”后，每个切片在人工唾液溶液（pH = 7.0）中孵育 4 周和 8 周，每天工作 1 小时在脱矿质溶液（pH = 4.3）中。对每个切片的横向显微射线照相术进行重拍，并确定“矿化损失后”。通过[1-（“矿化损失后”/“矿化损失前”）]×100%计算再矿化。使用具有一个重复测量的方差分析和一个组间因素（材料：ART 和 RM-GIC）的重复测量方差分析对结果进行统计分析（α=0.05）。