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亚利桑那阳光下的柠檬:呋喃香豆素导致植物性光皮炎和烧伤样损伤的影响。

Lemons in the Arizona Sunshine: The Effects of Furocoumarins Leading to Phytophotodermatitis and Burn-like Injuries.

作者信息

Matthews Marc R, VanderVelde Joel C, Caruso Daniel M, Foster Kevin N

机构信息

Arizona Burn Center, Department of Surgery, Maricopa Integrated Health System, Phoenix, AZ.

出版信息

Wounds. 2017 Dec;29(12):E118-E124.

Abstract

INTRODUCTION

Phytophototoxic dermatitis is a strong phototoxic reaction to ultraviolet A (UV-A) radiation exposure after cutaneous contact with citrus fruit containing furocoumarins, leading to skin injury. At the Arizona Burn Center (Phoenix, AZ), the majority of these injuries are managed in the outpatient setting.

CASE REPORT

The authors present a pediatric admission for burn-like injuries following prolonged cutaneous exposure to lemons while playing in the Arizona sunshine. A 7-year-old girl playing in her backyard squeezed lemon juice onto her skin while in the hot Arizona sunshine; within 24 hours, the child experienced pain, erythema, and blistering to multiple areas of her skin. She was admitted to the authors' burn center for wound care and pain control. She had scattered first-degree and second-degree burn-like lesions to her face, neck, and chest as well as bilateral forearms, hands, lower extremities, and feet. After blister debridement, appropriate dressing care, and pain medication, the patient was discharged home after 4 days of hospitalization with appropriate clinical follow-up.

CONCLUSIONS

Burn-like lesions caused by furocoumarins after cutaneous absorption and UV-A exposure are known clinical entities in Arizona. The sequential progression from erythema to blisters equivalent to second-degree burn-like lesions to cutaneous hyperpigmentation is a well-described clinical triad. Meticulous wound care and pain control for the treatment of these burn-like lesions are essential as is the need for the wound care specialist to be well versed on this topic to quickly identify the etiology of the injury, thereby avoiding misdiagnosing the patient with nonaccidental traumatic injuries.

摘要

引言

植物光毒性皮炎是皮肤接触含呋喃香豆素的柑橘类水果后,对紫外线A(UV-A)辐射产生的强烈光毒性反应,可导致皮肤损伤。在亚利桑那烧伤中心(亚利桑那州凤凰城),这些损伤大多在门诊处理。

病例报告

作者介绍了一名儿童因在亚利桑那州阳光下玩耍时长时间皮肤接触柠檬而出现类似烧伤的损伤并入院治疗的情况。一名7岁女孩在炎热的亚利桑那州阳光下在后院玩耍时,将柠檬汁挤到了自己皮肤上;24小时内,孩子的多处皮肤出现疼痛、红斑和水疱。她因伤口护理和疼痛控制被收治到作者所在的烧伤中心。她的面部、颈部、胸部以及双侧前臂、手部、下肢和足部有散在的一度及二度类似烧伤的皮损。经过水疱清创、适当的敷料护理和止痛药物治疗后,患者住院4天后出院,并进行了适当的临床随访。

结论

在亚利桑那州,皮肤吸收呋喃香豆素并暴露于UV-A后引起的类似烧伤的皮损是已知的临床病症。从红斑到相当于二度类似烧伤皮损的水疱再到皮肤色素沉着的连续进展是一种已被充分描述的临床三联征。对这些类似烧伤的皮损进行细致的伤口护理和疼痛控制至关重要,伤口护理专家也需要精通此主题,以便快速识别损伤的病因,从而避免将患者误诊为非意外创伤性损伤。

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