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腹壁下深动脉穿支皮瓣与植入物重建的效果:年龄真的有影响吗?

Outcomes in Deep Inferior Epigastric Perforator Flap and Implant-Based Reconstruction: Does Age Really Matter?

作者信息

Kuykendall Lauren V, Zhang Angie, Tugertimur Bugra, Bijan Sara, Agoris Corin, Kumar Ambuj, Dayicioglu Deniz

机构信息

1 Department of Surgery, Division of Plastic Surgery, University of South Florida, Morsani College of Medicine, Tampa, FL, USA.

2 University of South Florida, Morsani College of Medicine, Tampa, FL, USA.

出版信息

Cancer Control. 2018 Jan-Mar;25(1):1073274817744603. doi: 10.1177/1073274817744603.

Abstract

Despite the growing elderly population, there is limited research specific to this demographic concerning breast reconstruction (BR). Lack of evidence-based BR recommendations in older populations may contribute to misconceptions and subsequent underutilization of BR, especially autologous BR. Patients who received either deep inferior epigastric perforator (DIEP) flap BR or tissue expander/implant (TE/I) BR by a single surgeon between July 2011 and July 2015 were surveyed postoperatively by using the psychometrically validated BREAST-Q questionnaire to determine patient satisfaction. Patients were categorized into younger and older cohorts based on median age (55 years) and further stratified based on the type of reconstruction. Of the 311 patients surveyed, 95 patients responded (31% response rate). Overall, younger patients (<55 years old, n = 42) compared with older patients (≥55 years old, n = 53) had significantly higher satisfaction with their outcome (mean difference [MD] 12.06; 95% confidence interval [CI]: 0.96-23.15; P = 0.034). In the TE/I group (n = 58), younger patients had significantly higher satisfaction with breasts (MD: 14.17; 95% CI: 2.58-25.75; P = .017) and outcome (MD: 18.25; 95% CI: 3.95-32.5; P = .010) with fewer complications (odds ratio [OR]: 3.29; 95% CI: 1.37-7.86; P = .010). In the DIEP flap group (n = 55), there was no significant difference inr any of the satisfaction outcomes between younger and older patients. Younger patients tend to be more satisfied and demonstrate fewer complications with implant-based BR. In contrast, both younger and older patients undergoing abdominally based autologous BR were equally satisfied with comparable outcomes.

摘要

尽管老年人口不断增加,但针对这一人群的乳房重建(BR)的具体研究却很有限。老年人群中缺乏基于证据的BR建议可能会导致误解以及随后BR的利用不足,尤其是自体BR。2011年7月至2015年7月期间由同一位外科医生进行了腹壁下深动脉穿支(DIEP)皮瓣BR或组织扩张器/植入物(TE/I)BR的患者,术后使用经过心理测量验证的BREAST-Q问卷进行调查,以确定患者满意度。根据年龄中位数(55岁)将患者分为年轻组和老年组,并根据重建类型进一步分层。在接受调查的311名患者中,95名患者做出了回应(回应率为31%)。总体而言,与老年患者(≥55岁,n = 53)相比,年轻患者(<55岁,n = 42)对其结果的满意度显著更高(平均差异[MD] 12.06;95%置信区间[CI]:0.96 - 23.15;P = 0.034)。在TE/I组(n = 58)中,年轻患者对乳房的满意度显著更高(MD:14.17;95% CI:2.58 - 25.75;P = 0.017),对结果的满意度也更高(MD:18.25;95% CI:3.95 - 32.5;P = 0.010),并发症更少(比值比[OR]:3.29;95% CI:1.37 - 7.86;P = 0.010)。在DIEP皮瓣组(n = 55)中,年轻患者和老年患者在任何满意度结果上均无显著差异。年轻患者往往对基于植入物的BR更满意,且并发症更少。相比之下,接受基于腹部的自体BR的年轻患者和老年患者对可比结果的满意度相同。

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