Wierzbicka Małgorzata, Napierała Joanna
Department of Otolaryngology and Laryngological Oncology, Poznan University of Medical Science, Poznan, Poland.
Otolaryngol Pol. 2017 Dec 30;71(6):1-6. doi: 10.5604/01.3001.0010.7193.
The diagnostic and therapeutic recommendations have been changing over the years to improve treatment outcomes and quality of life of Head and Neck Cancer (HNC) patients.
The aim of this study was to present currently recommended Head and Neck Cancer treatment guidelines based on the literature review with particular emphasis on novel approaches the NCCN algorithms.
The review of literature covering articles published in the last five years and pointing out essential changes in HNC treatment regarding evidence based medicine. The study focused on the analysis of novel approaches for the particular primaries, the implementation of biological therapies and personalized cancer therapies.
Updates in the oncological NCCN guidelines for all ENT primaries except major salivary glands and subglottis are based on knowledge derived from the basic sciences, clinical trials and the best evidence available currently. The latest recommendations emphasize value of biological therapies use.
多年来，诊断和治疗建议一直在不断变化，以改善头颈癌（HNC）患者的治疗效果和生活质量。
本研究的目的是基于文献综述，介绍目前推荐的头颈癌治疗指南，特别强调NCCN算法中的新方法。
回顾过去五年发表的文献，指出基于循证医学的头颈癌治疗的重要变化。该研究重点分析了针对特定原发肿瘤的新方法、生物疗法的应用以及个性化癌症治疗。
除主要唾液腺和声门下区外，所有耳鼻喉原发肿瘤的肿瘤学NCCN指南更新均基于基础科学、临床试验和当前可得的最佳证据。最新建议强调了生物疗法使用的价值。
