BioDuro , No. 233 North FuTe Road, WaiGaoQiao Free Trade Zone, Shanghai 200131, P. R. China.
Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States.
Org Lett. 2018 Feb 2;20(3):812-815. doi: 10.1021/acs.orglett.7b03950. Epub 2018 Jan 12.
The design, synthesis, and application of [4-(acetylamino)phenyl]imidodisulfuryl difluoride (AISF), a shelf-stable, crystalline reagent for the synthesis of sulfur(VI) fluorides, is described. The utility of AISF is demonstrated in the synthesis of a diverse array of aryl fluorosulfates and sulfamoyl fluorides under mild conditions. Additionally, a single-step preparation of AISF was developed that installed the bis(fluorosulfonyl)imide group on acetanilide utilizing an oxidative C-H functionalization protocol.
设计、合成和应用[4-(乙酰氨基)苯基]亚氨基二硫代二氟化物（AISF），一种用于合成六价硫氟化物的稳定、结晶试剂，已被描述。AISF 的实用性已在温和条件下合成各种芳基氟硫酸盐和磺胺氟化物中得到证明。此外，还开发了一种单步制备 AISF 的方法，该方法利用氧化 C-H 功能化方案在乙酰胺上安装双（氟磺酰基）亚胺基。
