Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.
Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.
Cell. 2018 Jan 11;172(1-2):3-5. doi: 10.1016/j.cell.2017.12.034.
Trained immunity is a form of innate immune memory with distinct features from classical adaptive immune memory. In the current issues of Cell and Cell Host & Microbe, five studies from the International Trained Immunity Consortium shed light on mechanisms and functional consequences of this phenomenon on cellular and whole-organism levels.
训练免疫是一种先天免疫记忆形式,具有不同于经典适应性免疫记忆的特征。在本期的《细胞》和《细胞宿主与微生物》杂志上,来自国际训练免疫联合会的五项研究揭示了这一现象在细胞和整个机体水平上的机制和功能后果。