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从五叶瓜馥木(Retz.)叶提取物中生物合成、表征和评价氧化锌纳米粒子的抗菌活性。

Biosynthesis, characterization and antimicrobial activities of zinc oxide nanoparticles from leaf extract of Glycosmis pentaphylla (Retz.) DC.

机构信息

Computational Phytochemistry Lab, PG and Research Department of Botany and Microbiology, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur (Dist), Tamil Nadu, India.

Computational Phytochemistry Lab, PG and Research Department of Botany and Microbiology, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur (Dist), Tamil Nadu, India.

出版信息

Microb Pathog. 2018 Mar;116:44-48. doi: 10.1016/j.micpath.2018.01.003. Epub 2018 Jan 9.

DOI:10.1016/j.micpath.2018.01.003
PMID:29330059
Abstract

Biosynthesized nanoparticles have an incredible application in biomedicine owing to its simplicity, eco-friendly properties and low cost. The present study aims to determine the green synthesized zinc oxide nanoparticles from methanolic leaf extract of Glycosmis pentaphylla. The synthesized nanoparticles were characterized using UV-VIS Spectroscopy, Fluorescence spectrometer, FT-IR, XRD, SEM with EDAX and TEM. The confirmations of synthesized nanoparticles were characterized by peak at 351 and 410 nm in the UV-VIS spectrum and photoluminescence spectrum respectively. FT-IR studies revealed the functional group of the nanoparticles. The XRD data showed the crystalline nature of the nanoparticles and EDAX measurements indicated the 20.70% of highly pure zinc oxide metal. The morphological characterization of synthesized zinc oxide nanoparticles was analyzed by SEM and TEM and size of the particles were ranging from 32 to 36 nm. The synthesized zinc oxide nanoparticles exhibited interesting antimicrobial activity against pathogenic organisms. In addition, this is the first report on leaf mediated synthesis of zinc oxide (ZnO) nanoparticles from Glycosmis pentaphylla.

摘要

由于其简单、环保和低成本的特点,生物合成纳米粒子在生物医学中有令人难以置信的应用。本研究旨在从五叶甘橘的甲醇叶提取物中确定绿色合成的氧化锌纳米粒子。使用紫外-可见光谱、荧光光谱仪、傅里叶变换红外光谱、X 射线衍射、SEM-EDAX 和 TEM 对合成的纳米粒子进行了表征。在紫外-可见光谱和光致发光光谱中分别在 351 和 410nm 处的峰来确认合成的纳米粒子。FT-IR 研究表明了纳米粒子的官能团。XRD 数据显示了纳米粒子的结晶性质,EDAX 测量表明,高度纯净的氧化锌金属占 20.70%。通过 SEM 和 TEM 对合成的氧化锌纳米粒子的形态特征进行了分析,粒子的大小范围在 32 到 36nm 之间。合成的氧化锌纳米粒子对病原生物表现出有趣的抗菌活性。此外,这是首次从五叶甘橘中报道利用叶子介导合成氧化锌(ZnO)纳米粒子。

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