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Screening for obstructive sleep apnea in elderly: performance of the Berlin and STOP-Bang questionnaires and the Epworth sleepiness scale using polysomnography as gold standard.老年人阻塞性睡眠呼吸暂停的筛查：以多导睡眠图为金标准评估柏林问卷、STOP-Bang问卷及爱泼华嗜睡量表的效能
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Comparison of expiratory pressures generated by four different EPAP devices in a laboratory bench setting.在实验室台架环境下对四种不同呼气末正压（EPAP）设备产生的呼气压力进行比较。
Sleep Med. 2022 Aug;96:87-92. doi: 10.1016/j.sleep.2022.05.004. Epub 2022 May 13.
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Relationship Between CPAP Termination and All-Cause Mortality: A French Nationwide Database Analysis.CPAP 终止与全因死亡率的关系：法国全国数据库分析。
Chest. 2022 Jun;161(6):1657-1665. doi: 10.1016/j.chest.2022.02.013. Epub 2022 Feb 15.
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A comprehensive review of obstructive sleep apnea.阻塞性睡眠呼吸暂停的全面综述。
Sleep Sci. 2021 Apr-Jun;14(2):142-154. doi: 10.5935/1984-0063.20200056.
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Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association.阻塞性睡眠呼吸暂停与心血管疾病：美国心脏协会科学声明
Circulation. 2021 Jul 20;144(3):e56-e67. doi: 10.1161/CIR.0000000000000988. Epub 2021 Jun 21.
7
The effect of non-benzodiazepine sedative hypnotics on CPAP adherence in patients with OSA: a systematic review and meta-analysis.非苯二氮䓬类镇静催眠药对阻塞性睡眠呼吸暂停患者 CPAP 依从性的影响：系统评价和荟萃分析。
Sleep. 2021 Aug 13;44(8). doi: 10.1093/sleep/zsab077.
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10
Comparison of clinical and polysomnographic parameters between obese and nonobese obstructive sleep apnea.肥胖与非肥胖阻塞性睡眠呼吸暂停患者临床及多导睡眠图参数的比较
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阻塞性睡眠呼吸暂停：门诊环境中的筛查、管理及应对治疗挑战的策略

Obstructive Sleep Apnea: Strategies for Screening, Management, and Overcoming Treatment Challenges in the Outpatient Setting.

作者信息

Shah Radhika M, Sethi Jigme M, Wolf Larissa, LaCavera Margeaux, Koo Patrick

机构信息

Division of Respiratory, Critical Care, and Sleep Medicine, UTHSC College of Medicine - Chattanooga, Baroness Erlanger Hospital, Chattanooga, TN, USA (RMS, JMS, PK).

Division of Internal Medicine, UTHSC College of Medicine - Chattanooga, Baroness Erlanger Hospital, Chattanooga, TN, USA (LW, ML).

出版信息

Am J Lifestyle Med. 2023 Nov 24;19(5):664-675. doi: 10.1177/15598276231217949. eCollection 2025 Jul.

DOI:10.1177/15598276231217949
PMID:40548240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12177834/
Abstract

Obstructive sleep apnea (OSA) is characterized by repetitive airway closure, which can lead to hypoxemia and sympathetic nervous system activation. This can result in significant cardiovascular and neurologic morbidity. Therefore, early recognition and treatment are extremely important. The gold standard treatment of OSA is positive airway pressure, which has been shown to decrease the risk of these sequelae. Alternatives to positive airway pressure therapy are not commonly discussed but are available to those who are not able to tolerate positive airway pressure. The goal of this review is to discuss the pathophysiology, epidemiology, screening and testing, and treatment considerations for OSA.

摘要

阻塞性睡眠呼吸暂停（OSA）的特征是气道反复关闭，这可导致低氧血症和交感神经系统激活。这会导致严重的心血管和神经疾病。因此，早期识别和治疗极为重要。OSA的金标准治疗方法是气道正压通气，已证明其可降低这些后遗症的风险。气道正压通气治疗的替代方法较少被讨论，但对于无法耐受气道正压通气的患者是可行的。本综述的目的是讨论OSA的病理生理学、流行病学、筛查与检测以及治疗注意事项。