Villeneuve Alexandre, Rubin François, Bonfils Pierre
Service d'ORL, chirurgie cervico-faciale, hôpital Cochin, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France.
Service d'ORL, chirurgie cervico-faciale, hôpital Européen-Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France.
Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Apr;135(2):131-132. doi: 10.1016/j.anorl.2017.12.002. Epub 2018 Jan 10.
To report a case of marginal zone MALT lymphoma of the temporal dura mater, initially mistaken for temporal meningioma.
A 60-year-old immunocompetent woman, followed for more than 10 years for temporal meningioma causing vertigo and mixed hearing loss, presented with cervical lymphadenopathy, revealing marked progression of an intracranial lesion, leading to a diagnosis of marginal zone MALT lymphoma based on histological examination of a cervical lymph node. Treatment with 6 cycles of rituximab and bendamustine allowed complete remission of cervical lymph node and intracranial lesions, confirming the diagnosis of temporal dural mater lymphoma.
Primary dural lymphoma must be part of the differential diagnosis of meningioma. Long-term follow-up allows correction of the diagnosis.
报告一例颞部硬脑膜边缘区黏膜相关淋巴组织(MALT)淋巴瘤病例,该病例最初被误诊为颞部脑膜瘤。
一名60岁免疫功能正常的女性,因颞部脑膜瘤导致眩晕和混合性听力损失而接受随访超过10年,出现颈部淋巴结病,提示颅内病变明显进展,经颈部淋巴结组织学检查诊断为边缘区MALT淋巴瘤。接受6个周期的利妥昔单抗和苯达莫司汀治疗后,颈部淋巴结和颅内病变完全缓解,确诊为颞部硬脑膜淋巴瘤。
原发性硬脑膜淋巴瘤必须列入脑膜瘤的鉴别诊断。长期随访有助于修正诊断。