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痛风累及髌骨及膝关节伸肌机制,酷似侵袭性肿瘤。病例系列报道

Gouty involvement of the patella and extensor mechanism of the knee mimicking aggressive neoplasm. A case series.

作者信息

Kester Christopher, Wallace Matthew T, Jelinek James, Aboulafia Albert

机构信息

Department of Orthopaedics, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.

Orthopaedic Oncology, National Center for Bone and Soft Tissue Tumors, MedStar Franklin Square Medical Center, 9103 Franklin Square Drive Suite 2300, Baltimore, MD, 21237, USA.

出版信息

Skeletal Radiol. 2018 Jun;47(6):865-869. doi: 10.1007/s00256-017-2871-7. Epub 2018 Jan 14.

Abstract

Gout is a common inflammatory crystal deposition disease that occurs in many joints throughout the body. Active gout is most often associated with painful synovitis causing searing joint pains, but gout can also produce large masses of space-occupying deposits called tophi. Tophi are most frequently seen in juxta-articular locations with or without bony erosion and are often misdiagnosed as degenerative joint disease. Soft tissue deposits and tendon involvement are also known manifestations of gout, but can present with indeterminate and alarming findings on imaging. We present three cases of tophaceous gout mimicking aggressive neoplasms in the extensor mechanism of the knee. All cases presented as extensor tendon masses eroding into the patella, with imaging findings initially concerning for primary musculoskeletal malignancy.

摘要

痛风是一种常见的炎症性晶体沉积疾病,可发生于全身多个关节。活动期痛风最常与引起剧烈关节疼痛的疼痛性滑膜炎相关,但痛风也可产生大量称为痛风石的占位性沉积物。痛风石最常见于关节周围部位,伴或不伴有骨质侵蚀,常被误诊为退行性关节病。软组织沉积和肌腱受累也是痛风的已知表现,但在影像学上可能表现为不明确且令人担忧的发现。我们报告三例痛风石性痛风病例,其在膝关节伸肌机制中表现为侵袭性肿瘤。所有病例均表现为伸肌腱肿块侵蚀髌骨,影像学表现最初提示原发性肌肉骨骼恶性肿瘤。

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