Department of Radiology, Detroit Medical Center, 4201 St. Antoine, Detroit, MI, 48201, USA.
Department of Radiology, John D. Dingell VA Medical Center, 4646 John R St., Detroit, MI, 48201, USA.
Skeletal Radiol. 2020 Aug;49(8):1325-1328. doi: 10.1007/s00256-020-03422-y. Epub 2020 Mar 31.
Intraosseous gout involving the patella is an unusual presentation of the common inflammatory crystal deposition disease. In most reported cases of gout in the patella, there is prominent involvement of the adjacent patellar or quadriceps tendons of the extensor mechanism. A report from Japan describes another pattern of deposition, with a lesion arising in the synchondrosis of a bipartite patella. We present a case of a patient with no known history of gout experiencing vague anterior knee pain and subtle but rapidly progressive findings of a patellar lucent lesion on radiographs. No other cause for the patient's pain was identified on imaging. No prominent involvement of surrounding tendinous structures on MRI, unipartite patellar morphology, normal serum uric acid levels, rapid growth, and nonspecific appearance of the lesion led to a working diagnosis of patellar giant cell tumor. Biopsy of the lesion was performed to guide further management, which yielded the unexpected result of crystalline deposits consistent with gout.
累及髌骨的骨内痛风是一种不常见的常见炎症性晶体沉积病。在大多数报道的髌骨痛风病例中,相邻的髌骨或伸肌机制的股四头肌肌腱有明显受累。来自日本的一份报告描述了另一种沉积模式,病变发生在二分髌骨的联合处。我们报告了一例无已知痛风病史的患者,其出现模糊的前膝关节疼痛,且 X 线片上出现髌骨透亮病变,表现为细微但迅速进展。影像学检查未发现其他导致患者疼痛的原因。MRI 上无周围腱状结构明显受累、单发性髌骨形态、正常血清尿酸水平、病变快速生长和非特异性表现导致初步诊断为髌骨巨细胞瘤。对病变进行活检以指导进一步治疗,结果出人意料地发现了结晶沉积,符合痛风的表现。