Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Center for Health Research and Movement Science, College of Rehabilitation Sciences, University of Santo Tomas, Manila, Philippines.
Biomed Res Int. 2017;2017:2629310. doi: 10.1155/2017/2629310. Epub 2017 Nov 28.
Previous studies have explored the correlates of behavioural and autonomic regulation of response to sensory stimuli in children; however, a comprehensive review of such relationship is lacking. This systematic review was performed to critically appraise the current evidence on such relationship and describe the methods used in these studies.
Online databases were systematically searched for peer-reviewed, full-text articles in the English language between 1999 and 2016, initially screened by title and abstract, and appraised and synthesized by two independent review authors.
Fourteen Level III-3 cross-sectional studies were included for systematic review, among which six studies explored the relationship between behaviour and physiological regulation of responses to sensory stimuli. Three studies reported significant positive weak correlations among ASD children; however, no correlations were found in typically developing children. Methodological differences related to individual differences among participants, measures used, and varied laboratory experimental setting were noted.
This review suggests inconclusive evidence supporting the relationship between behavioural and physiological regulation of responses to sensory stimuli among children. Methodological differences may likely have confounded the results of the current evidence. We present methodological recommendations to address this matter for future researches. This trial is registered with PROSPERO registration number CRD42016043887.
之前的研究已经探讨了儿童对感觉刺激的行为和自主反应调节的相关性；然而，缺乏对这种关系的全面综述。本系统评价旨在批判性地评估这些研究中此类关系的现有证据，并描述这些研究中使用的方法。
系统地在线数据库搜索了 1999 年至 2016 年期间以英文发表的同行评审全文文章，最初通过标题和摘要进行筛选，然后由两位独立的审查作者进行评估和综合。
共纳入 14 项 III-3 级横断面研究进行系统评价，其中 6 项研究探讨了行为与对感觉刺激的生理反应调节之间的关系。三项研究报告 ASD 儿童之间存在显著的正弱相关；然而，在正常发育儿童中未发现相关性。注意到与参与者个体差异、使用的测量方法以及不同的实验室实验环境有关的方法学差异。
本综述表明，支持儿童对感觉刺激的行为和生理反应调节之间关系的证据尚无定论。方法学差异可能混淆了当前证据的结果。我们提出了方法学建议，以解决未来研究中的这一问题。本试验已在 PROSPERO 注册，注册号为 CRD42016043887。
