Department of Pharmacy, Xi'an Central Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Department of Respiratory, Xi'an Central Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Br J Clin Pharmacol. 2018 Apr;84(4):803-805. doi: 10.1111/bcp.13512. Epub 2018 Feb 9.
We describe the first case of Stevens-Johnson syndrome (SJS) occurring 8 days after the first dose of a three-dose rabies vaccination series. She had no history of vaccine-related rash or other adverse drug reactions, nor had she received any other drug therapy. The temporal relationship between the development of SJS and the vaccination suggests that the rabies vaccination probably was the causal agent. This case serves as a warning of a distinct cutaneous reaction of rabies vaccination.
我们描述了首例在接受三剂狂犬病疫苗系列的第一剂后 8 天发生的史蒂文斯-约翰逊综合征(SJS)病例。她没有疫苗相关皮疹或其他药物不良反应的病史,也没有接受过任何其他药物治疗。SJS 的发生与疫苗接种之间的时间关系表明,狂犬病疫苗可能是致病因素。该病例提醒人们注意狂犬病疫苗可能引起的明显皮肤反应。