Patel Ravi, Lu Victor
Department of Trauma and Orthopaedics, Hull Royal Infirmary, HU3 2JZ, Hull-United Kingdom.
2Department of Trauma and Orthopaedics, Addenbrooke's Hospital, CB2 0QQ-United Kingdom.
J Ayub Med Coll Abbottabad. 2023 Feb-Mar;35(1):180-181. doi: 10.55519/JAMC-01-11097.
We present a 23-year-old white British male that presented to the Accident and Emergency Department, two weeks after the second dose of the BNT162b2 (BioNTech/Pfizer) vaccine. No similar use has been documented previously in literature. We report one potential complication of the Pfizer COVID-19 vaccine: A known case of Stevens-Johnson syndrome (SJS) that occurred after the second dose of the Pfizer COVID-19 vaccine alone without exposure to any other drug. Despite a significantly severe adverse drug reaction, the patient demonstrated completed recovery. The risk of developing severe cutaneous drug reaction from subsequent COVID-19 vaccinations in these patients is still unclear and remains a dilemma to date.
我们报告一名23岁的英国白人男性，在接种第二剂BNT162b2（BioNTech/辉瑞）疫苗两周后前往急诊部。此前文献中未记载过类似病例。我们报告了辉瑞新冠疫苗的一种潜在并发症：一例已知的史蒂文斯-约翰逊综合征（SJS），该病例仅在接种第二剂辉瑞新冠疫苗后发生，未接触任何其他药物。尽管出现了严重的药物不良反应，但患者已完全康复。这些患者后续接种新冠疫苗发生严重皮肤药物反应的风险仍不明确，至今仍是一个难题。
