Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, Tanta University, Tanta, Egypt; Assistant Professor of Periodontology Department, College of Dentistry, Taibah University, Al Medinah, Kingdom of Saudi Arabia.
Assistant Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tanta University, Tanta, Egypt; Associate Professor of Oral and Maxillofacial Surgery, College of Dentistry, Taibah University, Al Medinah, Kingdom of Saudi Arabia.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Oct;132(4):e139-e142. doi: 10.1016/j.oooo.2021.06.019. Epub 2021 Jul 19.
Coronavirus disease 2019 (COVID-19) began in December 2019 and has affected millions of people all over the world. Respiratory illness in the form of severe pneumonia, in addition to multiorgan failure and death, is the clinical spectrum of COVID-19. Although there are no specific therapeutic agents for COVID-19 infection, the COVID-19 vaccine reduces morbidity and mortality associated with COVID-19 infection and is generally well tolerated. We report one potential complication of the Pfizer COVID-19 vaccine: a known case of Stevens-Johnson syndrome (SJS) that occurred after the second dose of the Pfizer COVID-19 vaccine alone without exposure to any other drug. Despite the initial severe adverse reaction, the patient showed a full recovery. Although SJS can be associated with COVID-19 vaccination, it is rare, and the benefits of receiving the vaccination outweigh the potential harms.
2019 年冠状病毒病（COVID-19）始于 2019 年 12 月，已影响到全世界数百万人。除多器官衰竭和死亡外，以严重肺炎为形式的呼吸道疾病是 COVID-19 的临床特征。尽管 COVID-19 感染没有特定的治疗药物，但 COVID-19 疫苗可降低 COVID-19 感染相关的发病率和死亡率，且通常具有良好的耐受性。我们报告了辉瑞 COVID-19 疫苗的一种潜在并发症：在单独接种第二剂辉瑞 COVID-19 疫苗后发生的已知 Stevens-Johnson 综合征（SJS）病例，且未接触任何其他药物。尽管最初出现严重不良反应，但患者完全康复。虽然 SJS 可能与 COVID-19 疫苗接种有关，但这种情况很少见，接种疫苗的益处大于潜在危害。
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