Xu Gang, Chen Ying, Liu Jie, Liu Shi-Wei, Wang Ping, Yang Jing, Huang Jiu-Ling
Department of Preventive Medicine, School of Basic Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2018 Jan;20(1):21-27. doi: 10.7499/j.issn.1008-8830.2018.01.005.
To study the burden of pediatric cancer in Jiangxi, China, in 2010 and 2015 and its changes from 2010 to 2015.
The data of pediatric cancer in Jiangxi in 2010 and 2015 were collected from the Global Burden of Disease Study 2015 in China, including number of cases, number of deaths, years of life lost (YLL), years lived with disability (YLD), and disability-adjusted life years (DALY). The standardized incidence rate, mortality rate, and DALY rate were calculated with the national census data in 2010 as the standard population, in order to evaluate the changes in incidence, mortality, and disease burden of pediatric cancer in Jiangxi.
In both 2010 and 2015, boys had higher numbers of cases, deaths, and DALY than girls, and the 5-14 years group had higher numbers than the 0-4 years group; boys had higher incidence rate, mortality rate, and DALY rate than girls, and the 0-4 years group had higher rates than the 5-14 years group. In 2015, the standardized incidence rate of pediatric cancer was reduced by 6.66% in the 0-4 years group and 17.56% in the 5-14 years group; the standardized mortality rate was reduced by 11.34% in the 0-4 years group and 21.78% in the 5-14 years group; the standardized DALY rate was reduced by 11.27% in the 0-4 years group and 21.67% in the 5-14 years group. Among the different types of pediatric cancer, leukemia had the highest standardized DALY rate in 2010 and 2015, followed by brain cancer and non-Hodgkin's lymphoma.
There was a certain reduction in the burden of pediatric cancer in Jiangxi from 2010 to 2015. Leukemia, brain cancer, and non-Hodgkin's lymphoma are the focus of prevention and treatment, and children aged less than 5 years and boys should be closely monitored.
研究2010年和2015年中国江西省儿童癌症负担及其从2010年到2015年的变化。
从《2015年中国全球疾病负担研究》中收集2010年和2015年江西省儿童癌症数据,包括病例数、死亡数、寿命损失年数(YLL)、带病生存年数(YLD)和伤残调整生命年数(DALY)。以2010年全国人口普查数据作为标准人群计算标准化发病率、死亡率和DALY率,以评估江西省儿童癌症发病率、死亡率和疾病负担的变化。
2010年和2015年,男孩的病例数、死亡数和DALY均高于女孩,5-14岁组高于0-4岁组;男孩的发病率、死亡率和DALY率高于女孩,0-4岁组高于5-14岁组。2015年,0-4岁组儿童癌症标准化发病率下降了6.66%,5-14岁组下降了17.56%;0-4岁组标准化死亡率下降了11.34%,5-14岁组下降了21.78%;0-4岁组标准化DALY率下降了11.27%,5-14岁组下降了21.67%。在不同类型的儿童癌症中,白血病在2010年和2015年的标准化DALY率最高,其次是脑癌和非霍奇金淋巴瘤。
2010年至2015年江西省儿童癌症负担有一定程度的减轻。白血病、脑癌和非霍奇金淋巴瘤是防治重点,5岁以下儿童和男孩应密切监测。