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[早产儿支气管肺发育不良药物治疗的研究进展]

[Research progress in drug therapy for bronchopulmonary dysplasia in preterm infants].

作者信息

Yang Yu-Chen, Mao Jian, Li Juan

机构信息

Department of Neonatology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2018 Jan;20(1):67-71. doi: 10.7499/j.issn.1008-8830.2018.01.014.

Abstract

Bronchopulmonary dysplasia (BPD) is the most common long-term complication in surviving extremely preterm infants. This may lead to pulmonary hypertension, increase late neonatal mortality, and cause abnormal neural development. There is still controversy over the efficacy, as well as advantages and disadvantages, of drug therapy for BPD in preterm infants. This article reviews the research progress in the drug therapy for BPD.

摘要

支气管肺发育不良(BPD)是存活的极早产儿最常见的长期并发症。这可能导致肺动脉高压,增加新生儿晚期死亡率,并引起神经发育异常。关于早产儿BPD药物治疗的疗效以及利弊仍存在争议。本文综述了BPD药物治疗的研究进展。

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本文引用的文献

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Inhaled and systemic steroid exposure and neurodevelopmental outcome of preterm neonates.早产儿吸入和全身使用类固醇激素与神经发育结局
J Matern Fetal Neonatal Med. 2018 Oct;31(20):2665-2672. doi: 10.1080/14767058.2017.1350644. Epub 2017 Jul 16.

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