Galvão-Moreira Leonardo Victor, de Andrade Cláudia Monteiro, de Oliveira Jéssica Francisca Fernandes, Bomfim Maria Rosa Quaresma, Figueiredo Patricia de Maria Silva, Branco-de-Almeida Luciana Salles
Oral Health Prev Dent. 2018;16(1):71-77. doi: 10.3290/j.ohpd.a39684.
To investigate salivary parameters of caries susceptibility in men and women in order to identify potential variations due to sexual dimorphism.
A total of 46 female and 24 male patients, aged 18-40 years, participated in this study. Unstimulated saliva was collected for the evaluation of flow rate, pH, secretory IgA, Snyder test scores, and Streptococcus mutans counts (confirmed by PCR assay). Statistical analysis included the Mann-Whitney, Kruskal-Wallis and Bonferroni tests, one-way ANOVA, and the Spearman correlation at a 5% significance level, followed by a general linear model and multiple linear regressions.
Female participants presented lower salivary pH values compared to males (p < 0.05), and different patterns of correlation among salivary parameters were found in men (p < 0.05) and women (p < 0.001). When comparing the variables according to Snyder test scores in men and women, there was a significant difference for S. mutans levels in the male group, and for pH and IgA in the female group (p < 0.05). Gender was found to be a predictor of salivary flow (R2 = 0.05; p < 0.05) and pH (R2 = 0.16; p < 0.001). In the female group, multiple regression showed several predictors for salivary flow rate, pH, IgA and Snyder test scores (p < 0.05), whereas no predictor was found in the male group (p > 0.05).
Different salivary patterns were observed in men and women, thus the implications of such findings for caries susceptibility require further investigation.
研究男性和女性龋齿易感性的唾液参数，以确定由于性别差异导致的潜在变化。
共有46名年龄在18 - 40岁的女性患者和24名男性患者参与了本研究。收集非刺激性唾液以评估流速、pH值、分泌型IgA、斯奈德试验评分和变形链球菌计数（通过聚合酶链反应测定确认）。统计分析包括曼-惠特尼检验、克鲁斯卡尔-沃利斯检验和邦费罗尼检验、单因素方差分析以及在5%显著性水平下的斯皮尔曼相关性分析，随后进行一般线性模型和多元线性回归分析。
与男性相比，女性参与者的唾液pH值较低（p < 0.05），并且在男性（p < 0.05）和女性（p < 0.001）中发现了唾液参数之间不同的相关模式。根据男性和女性的斯奈德试验评分比较变量时，男性组中变形链球菌水平存在显著差异，女性组中pH值和IgA存在显著差异（p < 0.05）。发现性别是唾液流速（R2 = 0.05；p < 0.05）和pH值（R2 = 0.16；p < 0.001）的预测因子。在女性组中，多元回归显示了唾液流速、pH值、IgA和斯奈德试验评分的几个预测因子（p < 0.05），而在男性组中未发现预测因子（p > 0.05）。
在男性和女性中观察到不同的唾液模式，因此这些发现对龋齿易感性的影响需要进一步研究。
