Department of Pediatrics, Division of Neonatology, LAC + USC Medical Center, Keck School of Medicine of University of Southern California, Los Angeles, CA; Division of Neonatology, Fetal and Neonatal Institute, Children's Hospital Los Angeles, Los Angeles, CA; Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Department of Pediatrics, Division of Neonatology, LAC + USC Medical Center, Keck School of Medicine of University of Southern California, Los Angeles, CA; Division of Neonatology, Fetal and Neonatal Institute, Children's Hospital Los Angeles, Los Angeles, CA; Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Semin Perinatol. 2018 Mar;42(2):68-79. doi: 10.1053/j.semperi.2017.12.002. Epub 2018 Jan 12.
Extracorporeal membrane oxygenation (ECMO), a life-saving therapy for respiratory and cardiac failure, was first used in neonates in the 1970s. The indications and criteria for ECMO have changed over the years, but it continues to be an important option for those who have failed other medical therapies. Since the Extracorporeal Life Support Organization (ELSO) Registry was established in 1989, more than 29,900 neonates have been placed on ECMO for respiratory failure, with 84% surviving their ECMO course, and 73% surviving to discharge or transfer. In this chapter, we will review the basics of ECMO, patient characteristics and criteria, patient management, ECMO complications, special uses of neonatal ECMO, and patient outcomes.
体外膜肺氧合（ECMO）是一种用于治疗呼吸和心脏衰竭的救生疗法，于 20 世纪 70 年代首次应用于新生儿。多年来，ECMO 的适应证和标准发生了变化，但对于那些其他医疗治疗失败的患者来说，它仍然是一个重要的选择。自 1989 年体外生命支持组织（ELSO）登记处成立以来，已有超过 29900 名新生儿因呼吸衰竭接受 ECMO 治疗，其中 84%的患者在 ECMO 疗程中存活，73%的患者存活至出院或转院。在本章中，我们将回顾 ECMO 的基础知识、患者特征和标准、患者管理、ECMO 并发症、新生儿 ECMO 的特殊用途和患者结局。
