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[汉赛巴尔通体:临床疑似猫抓病儿科患者的血清学证据]

[Bartonella henselae: Serological evidence in pediatric patients with clinical suspicion of cat scratch disease].

作者信息

Armitano Rita, Lisa Agustina, Martínez Claudia, Cipolla Lucia, Iachini Ricardo, Prieto Monica

机构信息

Servicio Bacteriología Especial, INEI-ANLIS «Dr. Carlos G. Malbrán», CABA, Argentina.

Instituto de Zoonosis «Luis Pasteur», CABA, Argentina.

出版信息

Rev Argent Microbiol. 2018 Oct-Dec;50(4):365-368. doi: 10.1016/j.ram.2017.10.004. Epub 2018 Jan 12.

Abstract

Cat scratch disease (CSD) is caused by Bartonella henselae, which mainly affects children. The cat is the reservoir. The laboratory diagnosis is based on the detection of antibodies by the Indirect Immunofluorescence (IFI) assay. The objective of this study was to analyze the serological evidence of B. henselae infection in pediatric patients that met the clinical/epidemiological criteria for suspected CSD. We studied 92 patients, who were categorized into four serological groups: 1) IgG (+)/IgM(+), 31,5% (n=29); 2) IgG (-)/IgM(+), 10,9% (n=10); 3) IgG (+)/IgM(-), 9,8% (n=9); 4) IgG (-)/IgM(-), 47,8% (n=44). These findings aim to promote future works for investigating the seroprevalence of Bartonella spp. in Argentina, which will allow us to know the importance of this zoonosis in our population and to evaluate new cut-off points of the technique.

摘要

猫抓病(CSD)由汉赛巴尔通体引起,主要影响儿童。猫是该病菌的储存宿主。实验室诊断基于间接免疫荧光(IFI)检测法检测抗体。本研究的目的是分析符合疑似CSD临床/流行病学标准的儿科患者中汉赛巴尔通体感染的血清学证据。我们研究了92例患者,他们被分为四个血清学组:1)IgG(+)/IgM(+),31.5%(n = 29);2)IgG(-)/IgM(+),10.9%(n = 10);3)IgG(+)/IgM(-),9.8%(n = 9);4)IgG(-)/IgM(-),47.8%(n = 44)。这些发现旨在推动未来关于调查阿根廷巴尔通体属血清流行率的研究工作,这将使我们了解这种人畜共患病在我国人群中的重要性,并评估该技术的新临界值。

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