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Ultraviolet irradiation of platelet concentrate abrogates lymphocyte activation without affecting platelet function in vitro.

作者信息

Kahn R A, Duffy B F, Rodey G G

出版信息

Transfusion. 1985 Nov-Dec;25(6):547-50. doi: 10.1046/j.1537-2995.1985.25686071428.x.

DOI:10.1046/j.1537-2995.1985.25686071428.x
PMID:2933854
Abstract

We studied the effect of ultraviolet (UV) radiation on platelet concentrates. Samples irradiated at 310 mm for 30 minutes at a dose of 1782 J per m2 showed no loss of platelet function in vitro as determined by adenosine diphosphate, collagen, or ristocetin-induced aggregation. Lymphocytes isolated from irradiated units were unable to act as responders or stimulators in a mixed-lymphocyte reaction. These data suggest that UV radiation of platelet concentrates may result in a cell suspension that is unable to evoke an immunological response.

摘要

相似文献

1
Ultraviolet irradiation of platelet concentrate abrogates lymphocyte activation without affecting platelet function in vitro.
Transfusion. 1985 Nov-Dec;25(6):547-50. doi: 10.1046/j.1537-2995.1985.25686071428.x.
2
Applications of ultraviolet light in the preparation of platelet concentrates.紫外线在血小板浓缩物制备中的应用。
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3
Ultraviolet irradiation of platelet concentrates: feasibility in transfusion practice.血小板浓缩物的紫外线照射：输血实践中的可行性。
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Platelet concentrates irradiated with ultraviolet light retain satisfactory in vitro storage characteristics and in vivo survival.经紫外线照射的血小板浓缩物保持了令人满意的体外储存特性和体内存活率。
Br J Haematol. 1990 Jun;75(2):240-4. doi: 10.1111/j.1365-2141.1990.tb02656.x.
5
Evaluation of a new UVB source for irradiation of platelet concentrates.
Br J Haematol. 1990 Aug;75(4):573-7. doi: 10.1111/j.1365-2141.1990.tb07801.x.
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Effect of ionizing radiation on platelet function in vitro.电离辐射对体外血小板功能的影响。
Acta Radiol Oncol. 1981;20(5):333-6. doi: 10.3109/02841868109130218.
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Platelet function in platelet concentrates and in whole blood.血小板浓缩物和全血中的血小板功能。
Anaesth Intensive Care. 1985 Nov;13(4):355-61. doi: 10.1177/0310057X8501300404.
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[Assessment of speed of an anti-platelet effect after two different doses of acetylsalicylic acid by flocculation].[通过絮凝法评估两种不同剂量乙酰水杨酸后抗血小板作用的速度]
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UV light-induced changes in washed pig platelets.紫外线诱导洗涤猪血小板的变化。
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Effective ultraviolet irradiation of platelet concentrates in teflon bags.特氟龙袋中血小板浓缩物的有效紫外线照射
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