The National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West) at University Hospitals Bristol NHS Foundation Trust, 9th Floor Whitefriars, Lewins Mead, Bristol, BS1 2NT, UK.
Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK.
Int J Equity Health. 2018 Jan 16;17(1):8. doi: 10.1186/s12939-018-0722-3.
Excessive drinking leads to poor absorption of nutrients and homeless problem-drinkers often have nutritionally inadequate diets. Depletion of nutrients such as vitamin B1 can lead to cognitive impairment, which can hinder efforts to reduce drinking or engage with services. This review aimed to assess effectiveness of interventions designed to prevent or treat malnutrition in homeless problem-drinkers.
We systematically searched nine electronic databases and 13 grey literature sources for studies evaluating interventions to improve nutrition in homeless populations, without regional or language restrictions. Screening for inclusion was done in duplicate. One reviewer extracted data and assessed risk of bias, and another checked the extractions. Primary outcomes were nutrition status/deficiency, liver damage, and cognitive function. Secondary outcomes included abstinence, comorbidities, resource use, acceptability and engagement with intervention. Results were synthesised narratively.
We included 25 studies (2 Randomised Controlled Trials; 15 uncontrolled before and after; 7 surveys; 1 case-control). Nine studies evaluated educational and support interventions, five food provision, and three supplement provision. Eight studies evaluated a combination of these interventions. No two interventions were the same, and all studies were at high risk of bias. Nutritional status (intake/ deficiency) were reported in 11 studies and liver function in one. Fruit and vegetable intake improved with some education and support interventions (n = 4 studies) but not others (n = 2). Vitamin supplements appeared to improve vitamin deficiency levels in the blood (n = 2). Free or subsidised meals (n = 4) and food packs (n = 1) did not always fulfil dietary needs, but were usually considered acceptable by users. Some multicomponent interventions improved nutrition (n = 3) but acceptability varied (n = 3). No study reported cost effectiveness.
The evidence for any one intervention for improving malnutrition in homeless problem-drinkers was based on single studies at high risk of bias. Various food and supplement provision interventions appear effective in changing nutritional status in single studies. Educational and multicomponent interventions show improved nutritional behaviour in some studies but not others. Further better quality evidence is required before these interventions can be recommended for implementation. Any future studies should seek the end user input in their design and conduct.
Registered with PROSPERO: CRD42015024247 .
过度饮酒会导致营养吸收不良,无家可归的酗酒者往往饮食中营养不足。维生素 B1 等营养物质的消耗会导致认知障碍,从而阻碍减少饮酒或接受服务的努力。本综述旨在评估旨在预防或治疗无家可归酗酒者营养不良的干预措施的有效性。
我们系统地检索了九个电子数据库和 13 个灰色文献来源,以评估改善无家可归人群营养状况的干预措施,无区域或语言限制。进行了两次重复筛选以确定纳入标准。一名审查员提取数据并评估偏倚风险,另一名审查员检查提取内容。主要结果是营养状况/缺乏、肝损伤和认知功能。次要结果包括戒酒、合并症、资源利用、对干预措施的接受度和参与度。结果以叙述性方式进行综合。
我们纳入了 25 项研究(2 项随机对照试验;15 项未对照的前后研究;7 项调查;1 项病例对照研究)。9 项研究评估了教育和支持干预措施,5 项研究评估了食物供应,3 项研究评估了补充剂供应。8 项研究评估了这些干预措施的组合。没有两项干预措施是相同的,所有研究都存在很高的偏倚风险。11 项研究报告了营养状况(摄入量/缺乏),1 项研究报告了肝功能。一些教育和支持干预措施(n=4 项研究)增加了水果和蔬菜的摄入量,但其他干预措施(n=2 项研究)并没有。维生素补充剂似乎改善了血液中的维生素缺乏水平(n=2 项研究)。免费或补贴餐(n=4)和食品包(n=1)并不总是满足饮食需求,但通常被使用者认为是可以接受的。一些多组分干预措施改善了营养状况(n=3),但接受度各不相同(n=3)。没有研究报告成本效益。
任何一项改善无家可归酗酒者营养不良的干预措施的证据都基于高偏倚风险的单项研究。各种食物和补充剂供应干预措施在单项研究中似乎能有效改变营养状况。一些研究表明,教育和多组分干预措施改善了营养行为,但其他研究并未如此。在这些干预措施能够得到推荐实施之前,需要进一步的高质量证据。任何未来的研究都应在设计和实施过程中征求最终用户的意见。
在 PROSPERO 注册:CRD42015024247。