针对无家可归或住房条件差的问题饮酒者预防或治疗营养不良的干预措施：系统评价方案
Interventions for preventing or treating malnutrition in problem drinkers who are homeless or vulnerably housed: protocol for a systematic review.
作者信息
Thorley Helen, Porter Katie, Fleming Clare, Jones Tim, Kesten Joanna, Marques Elsa, Richards Alison, Savović Jelena
机构信息
The National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West) at University Hospitals Bristol NHS Foundation Trust, 9th Floor Whitefriars, Lewins Mead, Bristol, BS1 2NT, UK.
School of Social and Community Medicine, University of Bristol, Bristol, UK.
出版信息
Syst Rev. 2015 Sep 29;4:131. doi: 10.1186/s13643-015-0114-3.
BACKGROUND
Problem alcohol drinking in homeless and vulnerably housed people can lead to malnutrition, which is associated with complications such as alcohol-related brain damage. Homeless alcohol drinkers are likely to have worse health outcomes and different nutritional needs compared with housed alcohol-drinking persons. It is not clear whether interventions to improve nutritional status in this population have been effective. The purpose of this review is to assess the effectiveness and cost-effectiveness of interventions for preventing or correcting micronutrient deficiencies and other forms of malnutrition and related comorbidities in this population.
METHODS/DESIGN: A systematic search for studies of a nutrition-based intervention applied in the homeless or vulnerably housed population with problem drinking will be conducted. The following electronic databases will be systematically searched for relevant studies: MEDLINE, EMBASE, Web of Science, PsycINFO, CAB abstracts, CINAHL, Cochrane Public Health Group Register and Cochrane Drugs and Alcohol Group Register. Screening of identified abstracts for relevance and assessment of papers for inclusion will be done in duplicate. One reviewer will extract data from the studies and assess quality, and this will be checked by another reviewer. Discrepancies will be resolved by consensus. The primary outcomes are (mal)nutrition status or micronutrient deficiencies or change in (mal)nutrition status or micronutrient deficiencies, measures of liver damage and cognitive function. Secondary outcomes include comorbidities, quality of life and functional scales, resources used to deliver treatment, uptake/acceptability of the intervention and engagement with treatment services. Results will be analysed descriptively, and, if appropriate, meta-analyses will be performed.
DISCUSSION
The results of this review should help to inform the development of effective interventions that can be implemented in the community to improve the health of homeless people who are problem drinkers.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO CRD42015024247.
背景
无家可归者及住房条件差的人群中存在的问题饮酒行为会导致营养不良，而这与诸如酒精相关脑损伤等并发症有关。与有住所的饮酒者相比，无家可归的饮酒者健康状况可能更差，营养需求也不同。目前尚不清楚改善该人群营养状况的干预措施是否有效。本综述的目的是评估预防或纠正该人群微量营养素缺乏及其他形式营养不良和相关合并症的干预措施的有效性和成本效益。
方法/设计：将系统检索针对有问题饮酒行为的无家可归者或住房条件差的人群实施的基于营养的干预措施的研究。将系统检索以下电子数据库以查找相关研究：医学期刊数据库（MEDLINE）、荷兰医学文摘数据库（EMBASE）、科学引文索引数据库（Web of Science）、心理学文摘数据库（PsycINFO）、国际农业与生物科学中心数据库（CAB abstracts）、护理学与健康照护领域数据库（CINAHL）、考克兰公共卫生组注册库以及考克兰药物与酒精组注册库。将对所识别的摘要进行重复筛选以确定相关性，并对论文进行重复评估以确定是否纳入。一名评审员将从研究中提取数据并评估质量，另一名评审员将进行核对。如有分歧，将通过协商解决。主要结局指标为（不）良营养状况或微量营养素缺乏情况，或（不）良营养状况或微量营养素缺乏情况的变化、肝损伤指标和认知功能。次要结局指标包括合并症、生活质量和功能量表、提供治疗所使用的资源、干预措施的接受度/可接受性以及与治疗服务的接触情况。将对结果进行描述性分析，如有合适情况，将进行荟萃分析。
讨论
本综述的结果应有助于为制定可在社区实施的有效干预措施提供信息，以改善有问题饮酒行为的无家可归者的健康状况。
系统综述注册
国际前瞻性系统评价注册库（PROSPERO）登记号CRD42015024247。
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