Laboratory of Nanomedicine, Institute of Life Sciences, Bhubaneswar 751023, Odisha, India.
Laboratory of Nanomedicine, Institute of Life Sciences, Bhubaneswar 751023, Odisha, India.
Int J Pharm. 2018 Mar 1;538(1-2):263-278. doi: 10.1016/j.ijpharm.2018.01.016. Epub 2018 Jan 12.
Nanotechnology has become the indispensable cutting edge science providing solutions to many problems associated with human being. The application of nanotechnology associated to human health "nanomedicine" has revolutionized the drug delivery system by providing improved pharmacological and therapeutic properties of drugs. These advantageous effects of drug loaded nanocarrier systems are embraced by the pharmaceutical industries for the development of different effective nanocarriers. Currently, several drug loaded nanoformulations are approved by the Food and Drug Administration (FDA), and some of them are undergoing clinical trials for the human use. In this review, we have discussed the progress achieved so far for various drug loaded nanoformulations along with few emerging nanoformulations that are about to enter into clinical trials.
纳米技术已成为不可或缺的前沿科学，为解决许多与人类相关的问题提供了方案。纳米技术在人类健康方面的应用——“纳米医学”，通过提高药物的药理学和治疗特性，彻底改变了药物输送系统。制药行业利用载药纳米载体系统的这些优势，开发出了不同的有效纳米载体。目前，美国食品和药物管理局（FDA）已经批准了几种载药纳米制剂，其中一些正在进行临床试验，以供人类使用。在这篇综述中，我们讨论了迄今为止各种载药纳米制剂的进展情况，以及一些即将进入临床试验的新兴纳米制剂。
