Department of Psychiatry, University of Valladolid, Valladolid, Spain.
Research Group on Clinical Neuroscience of Segovia (GINCS), Segovia, Spain.
Psychopathology. 2018;51(1):47-56. doi: 10.1159/000486204. Epub 2018 Jan 16.
BACKGROUND/AIMS: Cenesthopathy is mainly associated with schizophrenia; however, its neurobiological basis is nowadays unclear. The general objective was to explore clinical correlates of cenesthopathy and subjective cognitive complaints in schizophrenia.
Participants (n = 30) meeting DSM-IV criteria for psychotic disorder were recruited from a psychiatry unit and assessed with: Association for Methodology and Documentation in Psychiatry (AMDP) system, Positive and Negative Syndrome Scale, Frankfurt Complaint Questionnaire (FCQ), and the Bonn Scale for the Assessment of Basic Symptoms (BSABS). For quantitative variables, means and Spearman correlation coefficients were calculated. Linear regression following backward method and principal component analysis with varimax rotation were used.
83.3% of subjects (73.3% male, mean age, 31.5 years) presented any type of cenesthopathy; all types of cenesthetic basic symptoms were found. Cenesthetic basic symptoms significantly correlated with the AMDP category "fear and anancasm," FCQ total score, and BSABS cognitive thought disturbances. In the regression analysis only 1 predictor, cognitive thought disturbances, entered the model. In the principal component analysis, a main component which accounted for 22.69% of the variance was found.
Cenesthopathy, as assessed with the Bonn Scale (BSABS), is mainly associated with cog-nitive abnormalities including disturbances of thought initiative and mental intentionality, of receptive speech, and subjective retardation or pressure of thoughts.
背景/目的：感觉异常主要与精神分裂症有关；然而，其神经生物学基础目前尚不清楚。主要目的是探讨精神分裂症患者感觉异常与主观认知主诉的临床相关性。
从精神病学病房招募符合 DSM-IV 精神障碍标准的参与者（n=30），并进行以下评估：精神病学方法和文献协会（AMDP）系统、阳性和阴性综合征量表、法兰克福投诉问卷（FCQ）和波恩基本症状评估量表（BSABS）。对于定量变量，计算平均值和斯皮尔曼相关系数。采用向后法的线性回归和具有方差极大旋转的主成分分析。
83.3%的受试者（73.3%为男性，平均年龄 31.5 岁）存在任何类型的感觉异常；所有类型的感觉基本症状均存在。感觉基本症状与 AMDP 类别“恐惧和anancasm”、FCQ 总分和 BSABS 认知思维障碍显著相关。在回归分析中，只有 1 个预测因子，即认知思维障碍，进入模型。在主成分分析中，发现了一个主要成分，占方差的 22.69%。
使用波恩量表（BSABS）评估的感觉异常主要与认知异常有关，包括思维主动性和心理意向性、接受性言语、主观迟缓和思维压力的障碍。
