University of Milano-Bicocca, ASST Monza, San Gerardo Hospital, Monza, Italy.
University of Milano-Bicocca, AUSL Romagna, Infermi Hospital, Rimini, Italy.
Neurourol Urodyn. 2018 Jun;37(5):1711-1716. doi: 10.1002/nau.23487. Epub 2018 Jan 17.
The aim of the study was to identify in a pure stress urinary incontinence (SUI) population risk factors for recurrence after single-incision slings (SIS).
This retrospective study analyzed women with complaints of SUI symptoms and urodynamically proven SUI. Exclusion criteria were recurrent SUI, overactive bladder syndrome/detrusor overactivity, preoperative postvoid residual >100 mL, reduced urethral mobility (<10° at the Q-tip test), concomitant anterior prolapse >I stage and previous history of radical pelvic surgery. Objective cure rate was assessed with stress test.
A total of 192 patients were analyzed. Objective cure rate was obtained in 86.5% of patients. According to univariate analysis, recurrences had higher prevalence of severe ICIQ-SF score (≥18 points), higher prevalence of reduced urethral mobility (Qtip ≤30°), higher prevalence of low detrusor pressures during voiding phase (opening pressure <15 cmH O, pressure at maximum flow <20 cmH O, closing pressure <15 cmH O), and higher prevalence of postoperative complications According to multivariate analysis ICIQ-SF score ≥18 points (P = 0.02; OR = 2.7) and detrusor pressure at maximum flow <20 cmH O (P < 0.01; OR = 3.6) resulted as independent risk factors for SUI recurrence (Table 3). A trend was found for urethral mobility ≤30° (P = 0.07; OR = 2.2).
Our study identifies SUI severity expressed with ICIQ-SF scores and low detrusor pressure at maximum flow as independent risk factors for SUI recurrence after SIS implantation while only a trend was found for reduced urethral mobility. Therefore, preoperative assessment of symptoms and urodynamics evaluation may play a key role in improving preoperative counseling and tailoring surgical treatment.
本研究旨在确定在单纯压力性尿失禁(SUI)人群中,经单切口吊带术(SIS)治疗后复发的风险因素。
这是一项回顾性研究,分析了有 SUI 症状且尿动力学检查证实为 SUI 的女性患者。排除标准为复发性 SUI、膀胱过度活动症/逼尿肌过度活动、术前残余尿量>100ml、尿道移动度降低(Q-tip 试验时<10°)、合并前位脱垂>I 度和既往盆腔根治性手术史。采用尿失禁问卷简表(ICIQ-SF)评估客观治愈率。
共分析了 192 例患者。86.5%的患者获得了客观治愈率。根据单因素分析,复发患者的 ICIQ-SF 评分(≥18 分)较高,尿道移动度降低(Q-tip ≤30°)的发生率较高,排尿期逼尿肌压力较低(起始压<15cmH2O,最大尿流压<20cmH2O,关闭压<15cmH2O),术后并发症的发生率较高。多因素分析显示,ICIQ-SF 评分≥18 分(P=0.02;OR=2.7)和最大尿流压<20cmH2O(P<0.01;OR=3.6)是 SUI 复发的独立危险因素(表 3)。尿道移动度≤30°有显著相关性(P=0.07;OR=2.2)。
本研究确定了 ICIQ-SF 评分表示的 SUI 严重程度和最大尿流压时逼尿肌压力较低是 SIS 植入后 SUI 复发的独立危险因素,而尿道移动度降低仅呈显著相关性。因此,术前症状评估和尿动力学评估可能在改善术前咨询和定制手术治疗方面发挥关键作用。