Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China.
Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China.
Molecules. 2018 Jan 14;23(1):167. doi: 10.3390/molecules23010167.
It is well known that spirostane-type saponins show various bioactivities. In our on-going program of screening these kinds of constituents from natural products, was found to be rich in them, and nine new spirostanol saponins, Yucca spirostanosides A₁ (), A₂ (), B₁ (), B₂ (), B₃ (), C₁ (), C₂ (), C₃ (), and D₁ (), together with five known ones (-) were isolated from the plant. Their structures were elucidated by extensive spectroscopic methods, including 1D and 2D NMR and MS spectra, and comparing with published data.
众所周知，螺甾烷型皂苷具有多种生物活性。在我们正在进行的从天然产物中筛选这类成分的计划中，发现富含此类成分，从该植物中分离得到了 9 种新的螺甾烷醇皂苷，分别为 Yucca spirostanosides A₁ ()、A₂ ()、B₁ ()、B₂ ()、B₃ ()、C₁ ()、C₂ ()、C₃ ()和 D₁ ()，以及 5 种已知的 (-)。通过包括 1D 和 2D NMR 和 MS 光谱在内的广泛光谱方法，并与已发表的数据进行比较，阐明了它们的结构。
