Mathes B M, Douglass M C
J Am Acad Dermatol. 1985 Dec;13(6):947-51. doi: 10.1016/s0190-9622(85)70243-5.
Many cutaneous disorders are associated with acquired immunodeficiency syndrome. We prospectively evaluated eighteen patients with acquired immunodeficiency syndrome and twelve patients with the immunodeficiency syndrome-related complex for dermatologic disorders. A high prevalence of seborrheic dermatitis was found in patients with acquired immunodeficiency syndrome--83%, in comparison with 1% to 3% of historic control subjects. Patients with the related complex also had an increased incidence of 42%. Seborrheic dermatitis in this population was often more explosive, inflammatory, and severe than is usually seen in otherwise healthy patients. Severity of seborrheic dermatitis correlated with a poor overall prognosis in our patients. Additionally, seborrheic dermatitis may be one of the most common cutaneous manifestations of acquired immunodeficiency syndrome.
许多皮肤疾病与获得性免疫缺陷综合征相关。我们前瞻性地评估了18例获得性免疫缺陷综合征患者和12例免疫缺陷综合征相关综合征患者的皮肤疾病。在获得性免疫缺陷综合征患者中发现脂溢性皮炎的患病率很高——83%,相比之下,历史对照受试者的患病率为1%至3%。相关综合征患者的发病率也增加了42%。该人群中的脂溢性皮炎通常比其他健康患者中常见的更为严重、炎症性更强。脂溢性皮炎的严重程度与我们患者的总体预后不良相关。此外,脂溢性皮炎可能是获得性免疫缺陷综合征最常见的皮肤表现之一。