Venkatesh Ramesh, Gurav Prachi, Abhishek Dave Prachi, Gandhi Arpan
Department of Uvea, Retina and Vitreous, Dr. Shroff's Charity Eye Hospital, Delhi, India.
Department of Ocular Pathology, Dr. Shroff's Charity Eye Hospital, Delhi, India.
Ocul Oncol Pathol. 2017 Nov;3(4):324-327. doi: 10.1159/000472152. Epub 2017 May 12.
Tissue diagnosis with vitreous and/or retinal biopsy usually confirms the diagnosis of primary vitreoretinal lymphoma. Multiple imaging modalities like fundus fluorescein angiography, fundus autofluorescence, and optical coherence tomography have been used to support the diagnosis of vitreoretinal lymphoma. We report a case of a 74-year-old lady diagnosed with primary vitreoretinal lymphoma showing a novel fluorescein angiographic finding of capillary dropout. We hypothesize that this clinical finding on the fluorescein angiogram may be due to the occlusion of the retinal vasculature by the malignant tumor cells. This finding also suggests the possible intraocular invasion of the malignant lymphomatous cells into the inner retinal layers.
通过玻璃体和/或视网膜活检进行组织诊断通常可确诊原发性玻璃体视网膜淋巴瘤。多种成像方式，如眼底荧光血管造影、眼底自发荧光和光学相干断层扫描，已被用于辅助玻璃体视网膜淋巴瘤的诊断。我们报告一例74岁女性原发性玻璃体视网膜淋巴瘤病例，该病例显示出一种新的荧光血管造影表现，即毛细血管缺失。我们推测，荧光血管造影上的这一临床发现可能是由于恶性肿瘤细胞阻塞视网膜血管所致。这一发现还提示恶性淋巴瘤细胞可能已眼内侵犯至视网膜内层。
