2012-2016 年加拿大温哥华男同性恋、双性恋和其他男男性行为者中 HIV 预防用药的知晓和使用趋势。
Trends in Awareness and Use of HIV PrEP Among Gay, Bisexual, and Other Men who have Sex with Men in Vancouver, Canada 2012-2016.
机构信息
School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
The Momentum Health Study, 505-1200, Burrard St., Vancouver, BC, V6Z 1Z5, Canada.
出版信息
AIDS Behav. 2018 Nov;22(11):3550-3565. doi: 10.1007/s10461-018-2026-4.
Abstract
Gay, bisexual, and other men who have sex with men (gbMSM) are at the highest risk for HIV infection in British Columbia (BC). Pre-exposure prophylaxis (PrEP) has been recently licensed but is currently not publicly funded in BC. Using respondent-driven sampling, we recruited a cohort of gbMSM to complete a computer-assisted self-interview with follow-up every 6 months. Stratified by HIV status, we examined trends in awareness of PrEP from 11/2012 to 02/2016 and factors associated with PrEP awareness. 732 participants responded to the PrEP awareness question. Awareness of PrEP among HIV-negative men increased from 18 to 80% (p < 0.0001 for trend); among HIV-positive men, awareness increased from 36 to 77% (p < 0.0001). PrEP awareness was associated with factors related to HIV risk including sero-adaptive strategies and sexual sensation seeking. Eight HIV-negative men reported using PrEP. Low PrEP uptake highlights that PrEP access should be expanded for at-risk gbMSM in BC.
摘要
男同性恋者、双性恋者和其他与男性发生性关系的男性（男男性行为者）在不列颠哥伦比亚省（BC）面临最高的 HIV 感染风险。暴露前预防（PrEP）最近已获得许可，但在 BC 尚未得到公共资助。我们使用响应驱动抽样法招募了一组男男性行为者，让他们完成了一份计算机辅助的自我访谈，并每 6 个月进行一次随访。我们按 HIV 状况进行分层，从 2012 年 11 月到 2016 年 2 月，检查了 PrEP 意识的趋势，并分析了与 PrEP 意识相关的因素。732 名参与者回答了 PrEP 意识问题。HIV 阴性男性对 PrEP 的意识从 18%增加到 80%（趋势 p<0.0001）；HIV 阳性男性的意识从 36%增加到 77%（趋势 p<0.0001）。PrEP 意识与与 HIV 风险相关的因素有关，包括血清适应性策略和性感觉寻求。有 8 名 HIV 阴性男性报告使用了 PrEP。PrEP 使用率低表明，应扩大 BC 高危男男性行为者的 PrEP 准入。
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