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伴有反复哮喘加重和类固醇相关“荨麻疹”的慢性类圆线虫病

Chronic strongyloidiasis with recurrent asthma exacerbations and steroid-associated 'hives'.

作者信息

Weisenberg Scott A

机构信息

Department of Medicine, New York University School of Medicine, New York City, New York, USA.

出版信息

BMJ Case Rep. 2018 Jan 17;2018:bcr-2017-221877. doi: 10.1136/bcr-2017-221877.

Abstract

A 74-year-old man experienced worsening asthma for several years. Oral steroids were required on multiple occasions for asthma treatment. During his steroid courses, he developed a hive-like rash, which would resolve after completion of each steroid course. He was from Romania, and had lived in the USA for many years. Laboratory testing had shown eosinophilia. He was eventually diagnosed with strongyloidiasis by serology. Treatment with ivermectin led to marked improvement but not resolution of his long-term asthma. His hive-like rash, which was likely larva currens, did not recur with a subsequent steroid course. Improved recognition of strongyloidiasis, particularly in steroid-treated patients, is needed.

摘要

一名74岁男性多年来哮喘病情不断恶化。多次需要口服类固醇来治疗哮喘。在类固醇疗程期间,他出现了荨麻疹样皮疹,每次类固醇疗程结束后皮疹都会消退。他来自罗马尼亚,在美国生活多年。实验室检查显示嗜酸性粒细胞增多。最终通过血清学诊断为类圆线虫病。使用伊维菌素治疗后病情有显著改善,但他的长期哮喘并未痊愈。他的荨麻疹样皮疹(可能是匐行疹)在随后的类固醇疗程中未再出现。需要提高对类圆线虫病的认识,尤其是在接受类固醇治疗的患者中。

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