Martinez Eric, Sahni Sonu, Cheema Muhammad Ai, Iftikhar Asma
Department of Primary Care, Touro College of Osteopathic Medicine, New York, USA.
Department of Pulmonary and Critical Care Medicine, New York Presbyterian Hospital Queens, New York, USA.
BMJ Case Rep. 2018 Jan 17;2018:bcr-2017-222846. doi: 10.1136/bcr-2017-222846.
Kounis syndrome defined as the appearance of acute coronary syndrome in the context of an allergic reaction is a relatively rare phenomenon. There are three variants of this syndrome in which the patient presents with symptoms of an acute chest. Herein, we describe a case of an 83-year-old woman who demonstrated type I variant of Kounis syndrome in response to vancomycin administration. After initialisation of vancomycin, she became unresponsive and an ECG demonstrated ST changes consistent with inferior-lateral myocardial infarction. Once allergic stimulus was removed, ECG normalised. Differential diagnosis includes, myocardial infarctions, angina as well as intravascular stent thrombosis, which must all be ruled out. The patient was monitored and discharged soon thereafter.
库尼斯综合征定义为在过敏反应情况下出现急性冠状动脉综合征，是一种相对罕见的现象。该综合征有三种变体，患者会出现急性胸痛症状。在此，我们描述一例83岁女性患者，其在使用万古霉素后出现了I型库尼斯综合征。使用万古霉素后，她失去意识，心电图显示ST段改变，符合下侧壁心肌梗死。一旦去除过敏刺激，心电图恢复正常。鉴别诊断包括心肌梗死、心绞痛以及血管内支架血栓形成，所有这些都必须排除。患者接受监测，此后不久出院。
